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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 71 (1986), S. 344-346 
    ISSN: 1432-0533
    Keywords: Progressive supranuclear palsy ; Lewy body ; Parkinson's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An autopsy case is reported which revealed not only clinical and neuropathological features of progressive supranuclear palsy, but also the presence of large numbers of Lewy bodies in the brain stem nuclei and cerebral cortex. This case seems to be progressive supranuclear palsy with Lewy bodies distributed as in Parkinson's disease. Such case has not been previously reported.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 75 (1988), S. 345-353 
    ISSN: 1432-0533
    Keywords: Lewy body ; Immunocytochemistry ; Ubiquitin ; Paired helical filaments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The nature of Lewy bodies (LBs) in the brain stem and cerebral cortex in five cases of diffuse Lewy body disease and one case of Parkinson's disease with dementia were investigated immunocytochemically with various antibodies to cytoskeletal proteins, paired helical filaments (PHF) and ubiquitin. Antibodies to 200-kDa component of neurofilament, tau and PHF showed no significant reactions with most of LBs. Antibodies to high-molecular weight microtubule-associated proteins (HMWMAPs) moderately stained the periphery of a few of LBs. A monoclonal antibody to PHF (DF2) which recognizes ubiquitin, and polyclonal antibodies to ubiquitin immunostained virtually all of the typical and cortical LBs as intensely as Alzheimer's neurofibrillary tangles and senile plaque neurites: the periphery of LBs was darkly stained, whereas the central core of typical LBs and central zone of cortical LBs were less intensely stained or remained unstained. Immunoelectron microscopy of the LBs with DF2 revealed that immune reaction products were located on the filaments exclusively in the periphery of LBs, but not on those in the center. These findings suggest that both types of LBs are immunocytochemically indistinguishable despite some structural differences, and that peripherally located filaments in LBs are tagged with ubiquitin, an element required for the ATP-dependent proteolysis system in the cell. Antibodies to ubiquitin are the most useful marker of LBs ever known.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of statistical physics 31 (1983), S. 279-308 
    ISSN: 1572-9613
    Keywords: Chaos ; mapping ; invariant measure ; ergodicity ; band structure of chaos ; power spectrum of chaos ; critical behavior ; scaling law ; Frobenius-Perron operator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Chaotic behaviors of the tent map (a piecewise-linear, continuous map with a unique maximum) are studied analytically throughout its chaotic region in terms of the invariant density and the power spectrum. As the height of the maximum is lowered, successive band-splitting transitions occur in the chaotic region and accumulate to the transition point into the nonchaotic region. The timecorrelation function of nonperiodic orbits and their power spectrum are calculated exactly at the band-splitting points and in the vicinity of these points. The method of eigenvalue problems of the Frobenius-Perron operator is used. 2 m−1 critical modes, wherem = 1,2, 3, ..., are found which exhibit the critical slowing-down near the 2 m−1-band to 2 m -band transition point. After the transition these modes become periodic modes which represent the cycling of nonperiodic orbits among 2 m bands together with the periodic modes generated by the preceding band splittings. Scaling laws near the transition point into the nonchaotic region are investigated and a new scaling law is found for the total intensity of the periodic part of the spectrum.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of statistical physics 30 (1983), S. 649-679 
    ISSN: 1572-9613
    Keywords: Chaos ; mapping ; ergodic ; mixing ; time-correlation function ; chaos-chaos transition ; Frobenius-Perron operator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Successive band-splitting transitions occur in the one-dimensional map xi+1=g(xi),i=0, 1, 2,... withg(x)=αx, (0 ⩽x ⩽ 1/2) −αx +α, (1/2 〈x ⩽ 1) as the parameterα is changed from 2 to 1. The transition point fromN (=2n) bands to 2Nbands is given byα=(√2)1/N (n=0, 1,2,...). The time-correlation functionξ i=〈δxiδx0〉/〈(δx0)2,δxi≡ xi−〈xi〉 is studied in terms of the eigenvalues and eigenfunctions of the Frobenius-Perron operator of the map. It is shown that, near the transition pointα=√2,ξ i−[(10−4√2)/17] δi,0-[(10√2-8)/51]δi,1 + [(7 + 4√2)/17](−1)ie−yi, whereγ≡√2(α−√2) is the damping constant and vanishes atα=√2, representing the critical slowing-down. This critical phenomenon is in strong contrast to the topologically invariant quantities, such as the Lyapunov exponent, which do not exhibit any anomaly atα=√2. The asymptotic expression forξ i has been obtained by deriving an analytic form ofξ i for a sequence ofα which accumulates to √2 from the above. Near the transition pointα=(√2)1/N, the damping constant ofξ i fori ⩾N is given byγ N=√2(αN-√2)/N. Numerical calculation is also carried out for arbitrary a and is shown to be consistent with the analytic results.
    Type of Medium: Electronic Resource
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