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  • 1
    Digitale Medien
    Digitale Medien
    Gonadal regulation of GABAA receptors in the different brain areas of the male Japanese quail (1991)
    Springer
    Experimental brain research 87 (1991), S. 634-640 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Quantitative autoradiography ; GABAA receptors ; [3H] muscimol ; Saturation binding ; Gonadal steroids ; Male Japanese quail
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3H] muscimol (specific GABAA receptor ligand) binding in the male Japanese quail brain. In gonadally intact Japanese quail brains, [3H] muscimol revealed a heterogeneous distribution with high GABAA receptor levels in the cerebellum pars granularis (656 fmol/mg wet weight of tissue) and in the pars molecularis (405 fmol/mg wet weight of tissue). Low receptor levels were found in the nucleus preopticus anterior and the nucleus lateralis of the hypothalamic regions (〈220 fmol/mg wet weight of tissue) as well as thalamic nuclei such as rotundus and pretectalis (220–261 fmol/ mg wet weight of tissue). Castration resulted in [3H] muscimol binding changes in both brain areas that contain steroid receptors and brain areas devoid of steroid receptors. In fact, castration led to high binding levels in the preopticus anterior nucleus and in the anterior neostriatum area, brain areas that are known to contain gonadal steroid receptors. Castration also elevated [3H] muscimol binding in the hyperstriatum ventrale and reduced binding levels in the paleostriatum augmentatum and the stratum griseum centrale area; all of these areas are known to be devoid of gonadal steroid receptors. At this point it was also important to know whether the gonadal steroid effect is due to alterations in the number of binding sites (Bmax) and/or the affinity binding state (KD). The saturation binding study, dealing with some of the areas described above in brains of male quails castrated or castrated and treated with testosterone or estradiol, demonstrated that the steroid replacement therapy was responsible for the changes of the Bmax. Diminishing Bmax values were displayed in the hypothalamic preoptic area and the hyperstriatum ventrale of the male quail treated with testosterone and estradiol while a reduced Bmax was obtained in the anterior neostriatum of the quail treated with the former steroid. Our findings suggest that these steroids might control some centrally mediated behavior activities through effects on the maximum number of GABAA binding sites in the male Japanese quail.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00227088
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  • 2
    Digitale Medien
    Digitale Medien
    A Golgi study on the hypothalamus of amphibia (1977)
    Springer
    Cell & tissue research 178 (1977), S. 341-354 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Neuronal typology ; Amphibia ; Hypothalamus ; Golgi technique
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The neuronal typology in the hypothalamus of the frog and the crested newt was studied by the Golgi technique. In the newt, piriform, multipolar or cerebrospinal fluid (CSF)-contacting neurons of relatively primitive type, according to the classification of Ramón-Moliner, are encountered in the preoptic area. Moreover, magnocellular neurons are impregnated. In the frog the preoptic area shows a more varied typology. The posterior hypothalami of the frog and the newt exhibit mainly bipolar CSF-contacting and piriform neurons. These latter are generally “tufted”, but some bipolar of multipolar cells are encountered, especially in the frog. The simple anatomical organization of the amphibian hypothalamus corresponds well with the pattern of a “generalized” integrative area where multimodal sensory inputs converge — including visceral information from cerebrospinal fluid by means of hypothalamic CSF-contacting sensors — to regulate the neuroendocrine outflow.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00218699
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  • 3
    Digitale Medien
    Digitale Medien
    A Golgi study of the hypothalamus of Actinopterygii (1978)
    Springer
    Cell & tissue research 191 (1978), S. 433-447 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Posterior hypothalamus ; Golgi technique ; Actinopterygii ; Teleostei
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The posterior hypothalami of the polypteriform, Calamoichthys, and of the teleost, Anguilla, were studied by means of the Golgi technique. In Calamoichthys, the lateral lobes are not developed and the median lobe is simple. In Anguilla, the median (tuberal) lobe shows lophodendritic, CSF-contacting cells and horizontal cells in the periventricular grey and some reticular elements directed toward the cell-poor lateral areas. In the lateral lobes the periventricular grey is formed by multipolar neurons and a diffuse population of multipolar cells of uncertain identity. The nucleus diffusus lobi lateralis is formed by scarce multipolar neurons, often placed next to the external surface of the brain. The organization of the lateral lobes in Actinopterygii is reminiscent of highly developed integrative regions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00219807
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