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  • 1
    Electronic Resource
    Electronic Resource
    Electrophysiological evidence for a spinal antinociceptive action of dipyrone (1994)
    Springer
    Inflammation research 41 (1994), S. 62-70 
    Details
    ISSN: 1420-908X
    Keywords: Dipyrone ; Metamizol ; Spinal cord ; Afferent fibres ; Inflammatory pain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Electrophysiological experiments in anesthetized cats and rats were performed in order to study the effects of dipyrone on single afferent fibers from the knee joint and on spinal cord neurons with knee joint input. The neurons were activated and/or rendered hyperexcitable by an acute inflammation in the knee joint. In the joint nerve in cats, intravenous dipyrone (25–100 mg/kg) reduced ongoing activity in 10/12 thinly myelinated afferents but only in 1/10 unmyelinated afferents; the responses to movements of the inflamed knee were reduced in 8/10 thinly myelinated but only in 3/10 unmyelinated units. The reduction of activity was significant 20–30 min after application and was maximal at 60–180 min. In the spinal cord of spinalized cats, intravenous dipyrone (25–100 mg/kg) reduced ongoing activity and/or responses to pressure onto the inflamed knee in 14/16 neurons and in non-spinalized rats similar effects were seen in 10/11 neurons. Effects on spinal cord neurons started 5–10 min after application and were maximal after 20–40 min. These data show pronounced suppression of inflammation-induced nociception by dipyrone and they suggest that the spinal cord is a major site of action of this compound.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01986396
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Design of minimax robust filtering for an integrated GPS/INS system (1999)
    Springer
    Journal of geodesy 73 (1999), S. 407-411 
    Details
    ISSN: 1432-1394
    Keywords: Key words. Kalman filtering ; GPS/INS ; Uncertainty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract. The problem of navigation systems with uncertain noise is considered. A minimax robust filtering which can minimize the worst performance under noise uncertainties using the game theory is proposed. This new filter is applied to an integrated GPS/INS navigation system. A high dynamics aircraft trajectory is designed to test the new filter. The results show that minimax robust filtering performs better than standard Kalman filtering when noise parameters of an inertial measurement unit change their statistical properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001900050260
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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