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  • 1975-1979  (2)
  • Head regeneration  (1)
  • Rat paw  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 180 (1976), S. 287-295 
    ISSN: 1432-041X
    Keywords: Hydra ; Head regeneration ; Morphogenetic substances
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Hydra regenerating heads release at least two substances into the surrounding medium: one stimulates and one inhibits head formation. The inhibitor is released mainly during the first hour after cutting, the activator is released more slowly with a maximum in the second hour and with substantial release still during the following six hours. The release of both substances seems to be specific for head regeneration: it is not found in animals regenerating feet. The sequential release of these substances leads to the early changes observed at the cellular level during head regeneration inhydra: the inhibitor produces a decrease, the activator an increase in the mitotic activity of interstitial and epithelial cells, if assayed on intact animals. Head regeneration is blocked, if the release of the head activator is prevented. It is therefore suggested that these substances are necessary to initiate head regeneration inhydra.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-8580
    Keywords: Edema, traumatic ; Rat paw ; Ödem, traumatisches ; Rattenpfote
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Berichtet wird über ein Versuchsmodell, das es zuverlässig ermöglicht, am Beispiel des Rattenpfotentestes ein posttraumatisches Ödem mit hoher Volumenausbeute und sicherer Reproduzierbarkeit unter größtmöglicher Gewebeschonung zu erzeugen. Das Ödem wird durch Quetschen der Rattenhinterpfote unter standardisierten Bedingungen in einer Wringe mit gegenläufigen Holzwalzen induziert und volumetrisch gemessen. Die Ergebnisse werden diskutiert und denen anderer Versuchsmodelle gegenübergestellt.
    Notes: Summary A standardized reproducible technique is reported for inducing traumatic edema in the rat paw showing considerable swelling volume and low tissue damage. The edema is measured volumetrically subsequent to squashing the rat paw under standardized conditions in a wringing-machine with two wooden rollers. The technique is compared with other methods.
    Type of Medium: Electronic Resource
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