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  • 1
    Digitale Medien
    Digitale Medien
    Heterotopic bone formation induced by bone morphogenetic protein in mice with collagen-induced arthritis
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 186 (1992), S. 1362-1367 
    Details
    ISSN: 0006-291X
    Schlagwort(e): [abr] BMP; bone morphogenetic protein ; [abr] BSA; bovine serum albumin ; [abr] CIA; collageninduced arthritis ; [abr] CII; type II collagen ; [abr] HBF; heterotopic bone formation ; [abr] IL-1; interleukin-1 ; [abr] PBS; phosphate-buffered saline ; [abr] RA; rheumatoid arthritis
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81556-6
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Heterotopic bone formation induced by bone morphogenetic protein in mice with collagen-induced arthritis
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 186 (1992), S. 1362-1367 
    Details
    ISSN: 0006-291X
    Schlagwort(e): [abr] BMP; bone morphogenetic protein ; [abr] BSA; bovine serum albumin ; [abr] CIA; collageninduced arthritis ; [abr] CII; type II collagen ; [abr] HBF; heterotopic bone formation ; [abr] IL-1; interleukin-1 ; [abr] PBS; phosphate-buffered saline ; [abr] RA; rheumatoid arthritis
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81556-6
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 3
    Digitale Medien
    Digitale Medien
    Interleukin-6 (IL-6) production in carcinoma of the cervix (1996)
    Springer
    Archives of gynecology and obstetrics 258 (1996), S. 25-33 
    Details
    ISSN: 1432-0711
    Schlagwort(e): Interleukin-6 (IL-6) ; Carcinoma of the uterine cervix ; Histologic type ; Carcinogenesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight well differentiated SCC secreted a large amount (〉 1500 pg/48 h/106 cells) of IL-6 in nude mice. In contrast, poorly differentiated SCC cell lines and all of the 7 adenocarcinoma cell lines secreted a small amount (〈 500 pg/48 h/106 cells of IL-6). The expression of IL-6 mRNA of the cell lines correlated well with their IL-6 secretion potential. However, the expression of IL-6 receptor did not correlate with the IL-6 secretory potential. We also studied the IL-6 secretion of freshly isolated normal squamous epithelium and of dysplastic epithelium. In culture, two normal squamous epithelia secreted a large amount (〉 2000 pg/48 h/106 cells), whereas 8 dysplasia epithelia secreted an extremely small amount (〈 10 pg/48 h/106 cells). About one-third of patients with SCC had a raised serum IL-6 value. IL-6 production may help to differentiate between SCC and adenocarcinoma of the uterine cervix. IL-6 regulation seems to change in the course of SCC carcinogenesis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01370929
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Interleukin-6 (IL-6) production in carcinoma of the cervix (1995)
    Springer
    Archives of gynecology and obstetrics 258 (1995), S. 25-33 
    Details
    ISSN: 1432-0711
    Schlagwort(e): Key words: Interleukin-6 (IL-6) ; Carcinoma of the uterine cervix ; Histologic type ; Carcinogenesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight well differentiated SCC secreted a large amount (〉1500 pg/48 h/106 cells) of IL-6 in nude mice. In contrast, poorly differentiated SCC cell lines and all of the 7 adenocarcinoma cell lines secreted a small amount (〈500 pg/48 h/106 cells of IL-6). The expression of IL-6 mRNA of the cell lines correlated well with their IL-6 secretion potential. However, the expression of IL-6 receptor did not correlate with the IL-6 secretory potential. We also studied the IL-6 secretion of freshly isolated normal squamous epithelium and of dysplastic epithelium. In culture, two normal squamous epithelia secreted a large amount (〉2000 pg/48 h/106 cells), whereas 8 dysplasia epithelia secreted an extremely small amount (〈10 pg/ 48 h/106 cells). About one-third of patients with SCC had a raised serum IL-6 value. IL-6 production may help to differentiate between SCC and adenocarcinoma of the uterine cervix. IL-6 regulation seems to change in the course of SCC carcinogenesis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01370929
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    DNA polymorphisms in the ε- and γ-globin gene regions in asian macaques (1991)
    Springer
    Biochemical genetics 29 (1991), S. 189-202 
    Details
    ISSN: 1573-4927
    Schlagwort(e): DNA polymorphism ; ε-globin gene ; γ-globin gene ; macaques
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract DNA polymorphisms in the ε- and γ-globin gene regions in nine Asian macaques(Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, andM. assamensis) were examined using several different restriction endonucleases and the human ε and γIVS2 probes.M. fuscata andM. mulatta had highly polymorphic sites(BglII andHincII, respectively) in the ε-globin gene region. TheBamHI site in the γ-globin gene region was highly polymorphic inM. mulatta, while theBglII andHindIII sites in the γ-globin gene region were highly polymorphic inM. fuscata andM. mulatta. The presence of the γ-globin gene triplication was frequently observed inM. fuscata. The gain or loss of an additionalBglII site between two γ-globin genes in Asian macaques seems to be very meaningful for discussing genetic relationships among them.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02401812
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    DNA polymorphisms in the ε- and γ-globin gene regions in asian macaques (1991)
    Springer
    Biochemical genetics 29 (1991), S. 189-202 
    Details
    ISSN: 1573-4927
    Schlagwort(e): DNA polymorphism ; ε-globin gene ; γ-globin gene ; macaques
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract DNA polymorphisms in the ε- and γ-globin gene regions in nine Asian macaques(Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, andM. assamensis) were examined using several different restriction endonucleases and the human ε and γIVS2 probes.M. fuscata andM. mulatta had highly polymorphic sites(BglII andHincII, respectively) in the ε-globin gene region. TheBamHI site in the γ-globin gene region was highly polymorphic inM. mulatta, while theBglII andHindIII sites in the γ-globin gene region were highly polymorphic inM. fuscata andM. mulatta. The presence of the γ-globin gene triplication was frequently observed inM. fuscata. The gain or loss of an additionalBglII site between two γ-globin genes in Asian macaques seems to be very meaningful for discussing genetic relationships among them.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00554211
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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