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  • Articles: DFG German National Licenses  (4)
  • 1980-1984  (4)
  • 1955-1959
  • Hypothalamus  (2)
  • Chemistry  (1)
  • Nifedipine  (1)
Source
  • Articles: DFG German National Licenses  (4)
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Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Immunohistochemical demonstration of the localization of corticotropin releasing factor-containing neurons in the hypothalamus of mammals including primates (1982)
    Springer
    Anatomy and embryology 165 (1982), S. 303-313 
    Details
    ISSN: 1432-0568
    Keywords: CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Mammals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The presence of the CRF-containing neurons in the hypothalamus was investigated in four different species (cats, dogs, pigs, and monkeys) by the peroxidase-antiperoxidase technique using specific anti-serum to CRF. In all animals examined, CRF-containing perikarya were found mainly in the paraventricular and supraoptic nuclei, and a small number of the immunoreactive cells were observed in the accessory supraoptic nucleus and the lateral hypothalamic area. The size of the CRF-containing perikarya ranged from 20–35 μm in diameter. These findings suggest that the magnocellular paraventricular and supraoptic nuclei are the center not only of the classical neurosecretory system for the production of the posterior lobe hormones, but also that of the CRF neuronal system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305569
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Different responses of the isolated canine coronary artery superfused with blood or Krebs-Henseleit solution (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 156-158 
    Details
    ISSN: 1432-1912
    Keywords: Canine coronary artery ; Superfusion media ; Nifedipine ; Ca2+-channels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Responses of ring segments of the isolated canine coronary artery superfused with arterial blood from a donor dog were compared with responses of segments superfused with Krebs-Henseleit (K-H) solution. KCl (1–30 mg) caused contraction in a dose-dependent manner both in K-H solution- and in blood-superfused preparation. However, CaCl2 (1–100 mg) and nifedipine (0.1–30 μg) contracted and relaxed, respectively, only blood-superfused preparation but not K-H solution-superfused one. These results show that even in the same region of the coronary artery, different superfusates result in different responses to contracting or relaxing agents. This difference may be explained by the idea that Ca2+-channels are activated and endow basal tension in blood-superfused preparations, but not in K-H solution-superfused ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00500911
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemical identification of neurons containing corticotropin-releasing factor in the rat hypothalamus (1983)
    Springer
    Cell & tissue research 230 (1983), S. 239-246 
    Details
    ISSN: 1432-0878
    Keywords: CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A specific rabbit anti-CRF serum and the immunoperoxidase technique were used to show that CRF-containing neurons are mainly distributed in the paraventricular and supraoptic nuclei of the rat hypothalamus. In addition, immunoreactive neurons are scattered in other hypothalamic regions. These neurons are 20–30 μm in diameter. From the present and previous investigations it may be concluded that the hypothalamic magnocellular nuclei, i.e., paraventricular and supraoptic, and other hypothalamic accessory nuclei, are the producing sites not only for vasopressin and oxytocin, but also for corticotropin-releasing factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213802
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Pulse response in an immobilized-enzyme column: Theoretical method for predicting elution curves (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 22 (1980), S. 779-797 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A theoretical method for predicting the elution profile of a pulse response in an immobilized-enzyme column is proposed. The method is based on a mass balance model, which is extensively used in gel chromatography. To test the method, a pulse of sucrose solution was applied to a column of spherical acrylamide gel in which was entrapped invertase from yeast, and it was eluted with 0.05M acetate buffer at pH 5.0. The elution curves of the substrate and the product were in fairly good agreement with the theoretically calculated ones. The method was extended to the system of reversible as well consecutive reactions.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260220405
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    Paper (German National Licenses)
    Fulltext
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