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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Computing 40 (1988), S. 91-109 
    ISSN: 1436-5057
    Keywords: 65R20 ; 45L10 ; Integral equations ; Tikhonov regularization ; parameter selection method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung In dieser Arbeit betrachten wir eine besondere Variante endlich-dimensionaler Tikhonov-Regularisierung schlechtgestellter Operatorgleichungen. Konvergenzraten werden nachgewiesen und eine a-posteriori Parameterwahl wird hergeleitet, die optimale Konvergenzraten bezüglich des Datenfehlers und der endlich-dimensionalen Approximation liefert, ohne Information über die exakte Lösung zu benötigen. Schließlich präsentieren wir auch einige numerische Beispiele, bei denen lineare Splinefunktionen verwendet werden, die die theoretischen Ergebnisse bestätigen.
    Notes: Abstract In this paper we consider a particular variant of finite-dimensional Tikhonov regularization for ill-posed operator equations. Convergence rates are established and an a-posteriori parameter choice method is derived that leads to optimal convergence rates with respect to data errors and with respect to the finite-dimensional subspace, without using any information about the exact solution. Finally, using linear splines we present several numerical examples that confirm the theoretical results.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Numerische Mathematik 61 (1992), S. 311-334 
    ISSN: 0945-3245
    Keywords: 65R20
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary In this paper new multilevel algorithms are proposed for the numerical solution of first kind operator equations. Convergence estimates are established for multilevel algorithms applied to Tikhonov type regularization methods. Our theory relates the convergence rate of these algorithms to the minimal eigenvalue of the discrete version of the operator and the regularization parameter. The algorithms and analysis are presented in an abstract setting that can be applied to first kind integral equations.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2048
    Keywords: Acetolactate synthase ; Amino acid (branched chain) ; Arabidopsis ; Feedback regulation ; Mutant ; Valine resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A valine-resistant mutant line, VAL-2, ofArabidopsis thaliana (L.) Heynh. was identified by screening M 2 populations of ethylmethane-sulfonate-mutagenized seeds. The resistance was found to be due to a single, dominant, nuclear gene mutation. Assay of acetolactate synthase (ALS) indicated that the valine resistance in this mutant is caused by decreased sensitivity of ALS to the branched-chain amino acids, valine, leucine andisoleucine. A two fold decrease in apparentK m value for pyruvate of the mutant ALS enzyme was detected compared with that of the wild type. The sensitivity of the ALS enzyme to sulfonylurea, imidazolinone and triazolopyrimidine herbicides was not altered in the mutant. At the plant growth level the mutant was also resistant to valine plus leucine, but was sensitive to leucine orisoleucine alone. The mutant gene,var1, maps, or is very closely linked, toCSR1, the gene encoding acetolactate synthase inArabidopsis.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2048
    Keywords: Acetolactate synthase ; Amino acid (branched chain) ; Arabidopsis ; Feedback regulation ; Mutant ; Valine resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A valine-resistant mutant line, VAL-2, of Arabidopsis thaliana (L.) Heynh. was identified by screening M 2 populations of ethylmethane-sulfonate-mutagenized seeds. The resistance was found to be due to a single, dominant, nuclear gene mutation. Assay of acetolactate synthase (ALS) indicated that the valine resistance in this mutant is caused by decreased sensitivity of ALS to the branched-chain amino acids, valine, leucine and isoleucine. A two fold decrease in apparent K m value for pyruvate of the mutant ALS enzyme was detected compared with that of the wild type. The sensitivity of the ALS enzyme to sulfonylurea, imidazolinone and triazolopyrimidine herbicides was not altered in the mutant. At the plant growth level the mutant was also resistant to valine plus leucine, but was sensitive to leucine or isoleucine alone. The mutant gene, var1, maps, or is very closely linked, to CSR1, the gene encoding acetolactate synthase in Arabidopsis.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0878
    Keywords: Luteinizing hormone-releasing hormone ; Hypothalamus ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Utilizing the unlabeled antibody enzyme method, we report the distribution of hypothalamic elements immunoreactive with antibodies to luteinizing hormone-releasing hormone (LH-RH) in the rat. Immunostained elements, resembling neural processes, were distributed along a pathway corresponding to the tuberoinfundibular tract which appeared to terminate near vascular elements in the external layer of the preand post-infundibular median eminence. No cell bodies stained specifically for LH-RH. Similar topographic arrangements were noted (in coronal and sagittal sections) in diestrous females, ovariectomized females and a hypophysectomized male. The same results were obtained with three different preparations of antisera to LH-RH. Our studies agree with those of other investigators using immunohistochemical techniques as well as with localization studies of LH-RH in the hypothalamus using bioassay and radioimmunoassay. Our results suggest that the unlabeled antibody enzyme technique will have unique value for identifying and tracing fiber systems related to specific functions within the hypothalamus.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0878
    Keywords: Growth hormone-release inhibiting hormone ; Somatostatin ; Hypothalamus ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Utilizing the unlabeled antibody enzyme method, we investigated the distribution of hypothalamic elements immunoreactive with antibodies to growth hormonerelease inhibiting hormone (GH-RIH). Immunostained elements, resembling neural processes, are distributed along a pathway corresponding to a portion of the tuberoinfundibular tract. However, GH-RIH fibers are caudal, dorsal and medial to LH-RH fibers detected by the same technique. Similar topographic arrangements are noted in coronal and sagittal sections. Comparable results were obtained with two different preparations of antisera to GH-RIH. No cell bodies specifically stained by anti-GH-RIH were detected. Our data agree with those of other investigators using immunohistochemical techniques.
    Type of Medium: Electronic Resource
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