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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 53 (1975), S. 889-897 
    ISSN: 1432-1440
    Keywords: Thrombocyten ; Immunologie ; Physiopathologie ; Blood platelets ; immunology ; physiopathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary It is recognized that blood plaetelets with a peculiar cell membrane which carries numerous genetically determined immunogens, but is also intricately associated with the hemostatic process not only participate in immune reactions as a passive target cell, but also as an active functional cell. Pertinent results of animal experiments and of in vivo and in vitro investigations with human blood platelets are reviewed in the attempt to elucidate the role of immune reactions of platelets in the pathogenesis of various human bleeding disorders.
    Notes: Zusammenfassung Aufgrund der Besonderheiten der Thrombocytenmembran mit genetisch determinierten, immunogenen Merkmalen einerseits und hämostatischen Funktionen andererseits nehmen Blutplättchen an Immunreaktionen nicht nur passiv als Zielzelle, sondern auch aktiv als Funktionszelle teil. Es wird eine Übersicht über tierexperimentelle Befunde und Ergebnisse von bisher vorliegenden in vivo- und in vitro-Untersuchungen mit menschlichen Blutplättchen gegeben und die Bedeutung thrombocytärer Immunreaktionen für die Pathogenese von hämorrhagischen Diathesen erörtert.
    Type of Medium: Electronic Resource
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