ZIB

1

Electronic Resource

Plant pathotoxins from Alternaria citri: The major toxin specific for rough lemon plants

Gardner, J.M. ; Kono, Y. ; Tatum, J.H. ; [et al.]

Amsterdam : Elsevier

Phytochemistry 24 (1985), S. 2861-2867

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ISSN: 0031-9422

Keywords: Alternaria alternate pv. citri ; Citrus jambhiri ; Citrus limonia ; Rangpur lime ; Rutaceae ; brown spot disease ; dihydro-α-pyrone ; host-specific toxin. ; polyalcohol ; rough lemon

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(85)80015-7

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2

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Plant pathotoxins from Alternaria citri: The minor ACRL toxins

Kono, Y. ; Gardner, J.M. ; Suzuki, Y. ; [et al.]

Amsterdam : Elsevier

Phytochemistry 24 (1985), S. 2869-2874

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ISSN: 0031-9422

Keywords: ACRL-toxin ; Alternaria alternate pv. citri ; Alternaria citri ; Citrus jambhiri ; Citrus limonia ; Rangpur lime ; Rutaceae ; brown spot disease ; polyalcohol. ; rough lemon ; α-pyrone

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(85)80016-9

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3

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Plant pathotoxins from Alternaria citri: Stereochemistry of the major and minor toxins

Kono, Y. ; Gardner, J.M. ; Kobayashi, K. ; [et al.]

Amsterdam : Elsevier

Phytochemistry 25 (1985), S. 69-72

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ISSN: 0031-9422

Keywords: Alternaria citri ; C. reticulata, rough lemon ; Citrus jambhiri ; Rangpur lime ; X-ray crystallography. ; dihydro-α-pyrone ; host-specific toxin ; polyalcohol ; α-pyrone

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)94503-5

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4

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Insulin receptor gene mutation: A molecular genetical and funtional analysis

Makino, H. ; Taira, M. ; Shimada, F. ; [et al.]

Amsterdam : Elsevier

Cellular Signalling 4 (1992), S. 351-363

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ISSN: 0898-6568

Keywords: Insulin receptor ; acanthosis nigricans ; insulin receptor gene ; insulin resistance ; leprechaunism ; non-insulin-dependent diabetes ; obesity ; pedigree analysis ; phosphorylation ; tyrosine kinase

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Medicine

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0898-6568(92)90030-C

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5

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Abnormal messenger ribonucleic acid (mRNA) transcribed from a mutant insulin receptor gene in a patient with type A insulin resistance (1992)

Shimada, F. ; Suzuki, Y. ; Taira, M. ; [et al.]

Springer

Diabetologia 35 (1992), S. 639-644

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ISSN: 1432-0428

Keywords: Insulin receptor ; type A insulin resistance ; deletion ; polymerase chain reaction ; insulin receptor gene ; direct sequence ; mRNA

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary In a previous report on a 16-year-old Japanese girl with type A insulin resistance, we found that one allele of the insulin receptor gene was inherited from her mother and contained a 1.2 kilobase pair deletion which removed the 14th exon in the β subunit. We extended investigation of the proband and found the deletion between two Alu sequences. To determine the effect of the deletion on the level of transcription and the splicing pattern of messenger ribonucleic acid (mRNA), we synthesized the complimentary DNA and used the polymerase chain reaction to amplify the region which included the deleted area. The deletion shifted the reading frame, resulting in a termination codon after amino acid 867 (Glu), thereby producing a truncated insulin receptor without a transmembrane region and cytoplasmic domain. We also sequenced each of 22 exons of the insulin receptor gene but found no mutation in exons of the insulin receptor gene, except for deletion of exon 14 of the maternal allele. Thus, the proband is a heterozygote for a single mutant allele. Abnormal mRNA transcribed from the mutant allele resulted in a decrease in insulin binding.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00400255

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6

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Defects in insulin binding and receptor kinase in cells from a woman with type A insulin resistance and from her family (1991)

Suzuki, Y. ; Hashimoto, N. ; Shimada, F. ; [et al.]

Springer

Diabetologia 34 (1991), S. 86-92

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ISSN: 1432-0428

Keywords: Insulin receptor ; type A syndrome of insulin resistance ; insulin binding ; autophosphorylation ; kinase activity

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Defects in insulin receptor function lead to impairment of the insulin response. We treated a patient with the typical phenotype of type A syndrome of insulin resistance whose insulin receptor seemed to lack the transmembrane region and cytoplasmic domain. Hyperinsulinaemia and resistance to exogenous insulin were evident, and insulin binding to cells and uptake of 2-deoxyglucose into fibroblasts were greatly decreased. Molecular weight of the α-subunit of the insulin receptor was normal, but autophosphorylation and kinase activity were impaired. In the pedigree analysis, defects in insulin binding were also observed in the mother, maternal grandfather and two maternal aunts, corresponding with the abnormality of the insulin receptor gene and mild insulin resistance. In the mother, much the same kinase defects as were seen in the patient became evident. However, no relatives had clinical symptoms similar to those seen in the patient. In the father there was a mild insulin resistance in the glucose clamp study and a borderline impaired glucose tolerance. Although insulin binding to cells was normal in the father, both autophosphorylation and kinase activity were reduced. Our findings suggest that insulin resistance in the patient may be caused by the defects in insulin receptor kinase activity as well as by a reduction in insulin binding activity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00500378

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7

Electronic Resource

Multiple urinary isoenzyme assay by high-performance liquid chromatography (1986)

Matsukura, H. ; Suzuki, Y. ; Okada, T. ; [et al.]

Weinheim : Wiley-Blackwell

Journal of High Resolution Chromatography 9 (1986), S. 479-480

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ISSN: 0935-6304

Keywords: High-performance liquid chromatography, HPLC ; Alkaline phosphatase, AP ; Lactate dehydrogenase, LD ; γ-Glutamyltransferase ; γ-GT ; Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Additional Material: 1 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jhrc.1240090817

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8

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Micro high performance liquid chromatography of aliphatic amines by means of resonance raman detection (1987)

Koizumi, H. ; Suzuki, Y.

Weinheim : Wiley-Blackwell

Journal of High Resolution Chromatography 10 (1987), S. 173-176

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ISSN: 0935-6304

Keywords: Micro high performance liquid chromatography, micro-HPLC ; Resonance Raman detection ; Dabsylamide ; Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: A micro high performance liquid chromatography coupled with a resonance Raman detection system is described. For highly sensitive Raman detection, aliphatic amines were derivatized with dabsyl chloride (4-dimethylaminoazobenzene-4′-sulfonyl chloride). The derivatives were separated on an ODS micro column (0.5 mm i.d. × 145 mm PTFE tube). Chromatograms were obtained by measuring the intensity of Raman scattering at 1136 cm-1 with the 488.0 nm line of an Arion laser. The lower detection limit was 1.5 ng and the RSD of relative peak height (n = 9) was 5.9% at 11 ng of methylamine derivative. Moreover, by stopping the flow of the micro HPLC system at the retention time of the individual derivatives, it was possible to measure their resonance Raman spectra.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jhrc.1240100403

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9

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Simultaneous analysis for acid phosphatase and alkaline phosphatase by ion-exchange liquid chromatography (1987)

Matsukura, H. ; Suzuki, Y. ; Okada, T. ; [et al.]

Weinheim : Wiley-Blackwell

Journal of High Resolution Chromatography 10 (1987), S. 108-109

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ISSN: 0935-6304

Keywords: Ion-exchange liquid chromatography ; Acid phosphatase ; Alkaline phosphatase ; Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jhrc.1240100215

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10

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The effect of oxidation state on the intensities of Kβ5 and Kβ″ of 3d-transition elements (1975)

Asada, E. ; Takiguchi, T. ; Suzuki, Y.

New York, NY [u.a.] : Wiley-Blackwell

X-Ray Spectrometry 4 (1975), S. 186-189

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ISSN: 0049-8246

Keywords: Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Physics

Notes: Using a commercially available flat crystal spectrometer in a slightly modified form, an investigation was made of the peak intensity ratios (Kβ5/Kβ1) and the relative intensities of Kβ″ to Kβ5 in different oxidation states of 3d-transition metal atoms existing in forms of oxidic compounds. The peak intensity ratios (Kβ5/Kβ1) for V, Cr, Mn, Fe, Co, Ni and Cu, as well as the peak profiles of Kβ″ and Kβ5 for V, Cr and Mn, were investigated. Results suggest that changes in the intensities of the Kβ5 and Kβ″ bands can be applied to determining the oxidation number of a metal atom in its oxide.

Additional Material: 4 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/xrs.1300040408

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