ISSN:
1432-2307
Keywords:
Keywords Lymphomatous polyposis
;
T-cell lymphoma
;
Intestinal lymphoma
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report an interesting case of primary intestinal T-cell lymphoma (ITL) resembling lymphomatous polyposis (LP) in a 24-year-old man. The neoplasm macroscopically showed numerous small polyps throughout the colon and microscopically showed diffuse proliferation of small-sized tumor cells with occasionally cleaved or irregularly shaped nuclei. The tumor cells were immunohistochemically positive for CD3, CD8, TIA-1, and CD56, and a polymerase chain reaction study showed a single band, indicating monoclonal rearrangement of the T-cell receptor β gene. The phenotypic features in the current case are consistent with those of ITL derived from cytotoxic CD56+CD8+ intraepithelial lymphocytes. This is the second documented case of primary ITL with a morphologic pattern of LP.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004280000270
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