ISSN:
1432-1076
Keywords:
Key words: Neonatal allo-immune thrombocytopenia – HPA-1 b – HLA class-I and class-II molecules
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract. We report a case of neonatal allo-immune thrombocytopenia due to fetomaternal human platelet antigen (HPA)-1 incompatibility. Anti-HPA-1 b antibodies were detectable in maternal serum. Repeated treatment of the infant with high-dose IgG effectively raised platelet counts transiently, but the patient remained thrombocytopenic for more than 6 weeks. Serological and DNA analysis revealed that the mother was homozygous HPA-1 a and the father homozygous HPA-1 b.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01959215
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