Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1435-1285
    Keywords: Schlüsselwörter Arteria thoracica interna-Bypass – Dopplersonographie – prä- und postoperative Diagnostik ; Key words Internal thoracic artery graft – Doppler ulltrasonography – pre- and postoperative diagnostic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary During the last 25 years the internal thoracic artery has become a well established conduit for coronary revascularization. Next to angiography, duplex-sonography is increasingly used as a non-invasive imaging procedure for the evaluation of this graft vessel. Preoperative investigation in 117 patients has yielded a high level of agreement between angiography and duplex-sonography. While the preoperative flow-pattern is dominated by systolic flow as it is typical for vessels supplying skeletal muscule, the postoperative findings show an adaptation to the coronary vascular bed as the diastolic flow increases. These non-invasive measurements are well matched with invasive intravascular recordings. Coronary angiography and duplex-sonography of the internal thoracic artery yielded comparable findings in respect to the procedural result. Considering the increasing use of the internal thoracic artery in coronary artery bypass surgery, this non-invasive method should gain increasing relevance.
    Notes: Zusammenfassung Die Verwendung der Arteria thoracica interna zur koronaren Revaskularisierung hat sich in den letzten 25 Jahren als Gefäß der Wahl etabliert. Neben dem etablierten Verfahren der Angiographie wird in den letzten Jahren die Duplexsonographie zunehmend als nicht invasives bildgebendes Verfahren zur Untersuchung dieses Gefäßes eingesetzt. Bei der präoperativen Evaluierung von 117 Patienten konnte im Vergleich zur Angiographie bei einem hohen Anteil der Patienten ein übereinstimmendes Untersuchungsergebnis festgestellt werden. Während in der präoperativen Phase das Strompulskurvenprofil entsprechend der arteriellen Versorgung eines Skelettmuskels durch einen hohen systolischen Anteil dominiert wird, kommt es zu einer postoperativen Anpassung an das koronararterielle Strombett in Form eines vermehrten diastolischen Flußanteils. Diese nicht invasiven Befunde der transthorakalen Duplexsonographie konnten durch invasive intravaskuläre Dopplermessungen bestätigt werden. Ebenso wie beim präoperativen Vergleich ergibt sich auch postoperativ ein hohes Maß an Übereinstimmung zwischen Angiographie und Duplexsonographie bei der Beurteilung des Revaskularisationsergebnisses. Im Hinblick auf die zunehmende Verwendung der Arteria thoracica interna als Bypassgefäß sollte dieses nicht invasive Verfahren zunehmend an Bedeutung gewinnen.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Planta 142 (1978), S. 83-90 
    ISSN: 1432-2048
    Keywords: Mitochondria ; NADH oxidation ; Rotenone-resistant respiration ; Vicia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Mitochondria from Vicia faba L. exhibit two pathways for the oxidation of endogenous NADH. One pathway is rotenone-sensitive and includes three phosphorylation sites, the other one is rotenone-insensitive and by-passes site I. This by-pass is located in the area of flavoproteins, but several lines of evidence suggest that the rotenone-insensitive oxidation of matrix-NADH is not mediated by the external NADH dehydrogenase. With saturating substrate concentrations the two pathways are superimposed in state 3 while in state 4 the electrons are transferred only via the by-pass. The rotenone-resistant electron flux is obviously regulated from the substrate side. We suggest that the function of the by-pass is to regulate the NADH/NAD+ ratio of the matrix space.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Planta 144 (1979), S. 359-365 
    ISSN: 1432-2048
    Keywords: Mitochondria ; NADH oxidation ; Respiration (rotenone-resistant) ; Temperature activation ; Vicia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract 1. Respiration rates of broad-bean (Vicia faba) mitochondria were studied as a function of temperature. Arrhenius plots of all membrane-bound enzymes, as obtained with saturating substrate concentrations, revealed a break in the lower temperature range. That break was considered to indicate a phase transition of membrane phospholipids, characteristic for chilling-sensitive plants. A second discontinuity at 30°C occurred only with activities linked to energy conservation. — 2. The activation energies for the oxidation of NAD+-linked substrates differ between states 3 and 4. State 3 respiration of NAD+-linked substrates is the result a superimposition of two branches of electron transport, which can be separated by different sensibilities to rotenone. A characteristic temperature dependency of the respiratory control, as well as a shift of the low temperature break in the Arrhenius plot toward a higher temperature after state 4 to state 3 transition, are calculated to be caused by the superimposition of the two branches. — 3. The temperature dependency of the oxidation of extra-mitochondrial NADH and of succinate differs remarkably from that of the oxidation of matrix-NADH. It has been concluded that the rotenone-resistant oxidation of matrix-NADH and the oxidation of external NADH are mediated via different pathways with individual regulation sites.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...