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  • History of psychiatry  (1)
  • Key words Pharmacotherapy – obesity – appetite suppressant – thermogenesis  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 67 (1996), S. 947-952 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Hermann F. Hoffmann ; Nationalsozialismus ; Biologismus ; Psychiatriegeschichte ; Key words Hermann F. Hoffmann ; National Socialism ; Biologism ; History of psychiatry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary This study covers the life and scientific work of Hermann F. Hoffmann who was a disciple of Robert Gaup and in 1936 took over from him as head of the psychiatric clinic at the University of Tübingen. As a scientist, Hoffmann was especially involved in research into genetic problems in psychiatry. He introduced a new approach to some premises of the so-called Tübingen Psychiatric School. In 1933, he joined the NSDAP and became one of the most prominent members of the National Socialist party at the University of Tübingen. From then on, he saw himself as a prophet of a new “biological” philosophy of life. From the present point of view, Hoffmann is something of a contradiction. On the one hand, he was a good doctor and a serious scientist; on the other, he promoted biologistic ideology and a criminal regime. These biographical inconsistencies point to some inconsistencies in the history of psychiatry itself with its dialectics of philanthropy and discrimination.
    Notes: Zusammenfassung Es wird ein Überblick über das Leben und das wissenschaftliche Werk Hermann F. Hoffmanns gegeben. Hoffmann war als Schüler und Nachfolger Robert Gaupps von 1936–1944 Direktor der Tübinger Universitätsnervenklinik. Wissenschaftlich befaßte er sich besonders mit Fragen der psychiatrischen Vererbungslehre, wobei er auf eine originelle Weise Grundpositionen der sog. Tübinger Schule variierte. Nach seinem NSDAP-Beitritt 1933 gehörte Hoffmann zu den einflußreichsten Nationalsozialisten an der Universität Tübingen. Er verstand sich nunmehr als Wegbereiter einer neuen, „biologischen“ Weltanschauung. Aus heutiger Sicht erscheint die Person Hoffmanns merkwürdig gebrochen. Neben traditioneller ärztlicher Haltung und ernsthafter Wissenschaftlichkeit findet man bei ihm biologistisches Denken und Engagement für ein verbrecherisches Regime. Diese biographischen Widersprüche weisen auf Widersprüche in der Geschichte der Psychiatrie selbst hin mit ihrer Dialektik von Humanität und Ausgrenzung.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 38 (1999), S. 1-13 
    ISSN: 1436-6215
    Keywords: Key words Pharmacotherapy – obesity – appetite suppressant – thermogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Notes: Summary Many new substances are currently being investigated for their usefulness in the pharmacotherapy of obesity. Most drugs interfere with monoamine neurotransmitter (serotonin, noradrenalin, dopamine and histamine) effects and act as an appetite suppressant. Other approaches are to primarily increase thermogenesis (e.g. β3-adrenoceptor agonists), or to decrease fat absorption by inhibiting the pancreatic lipase (orlistat). New promising agents are substances that increase the effect of corticotropin releasing factor (CRF) or urocortin in the brain (CRF-binding protein ligand inhibitor) and a neuropeptide Y (NPY) Y5 receptor antagonist. The clinical relevance of leptin in the therapy of obesity is probably limited, but can not be fully evaluated at the moment. As obesity has a multifactorial basis, all these substances have in common the fact that they can not cure obesity. They should only be used as an adjunct to classical strategies like diet and exercise in severe obesity. For developing new, perhaps even more specific pharmacological agents, further research is needed to understand the individually different genetic and physiological basis of obesity.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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