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  • Iron metabolism  (1)
  • Keywords: Spontaneous subdural haematoma; chronic subdural haematoma; subacute subdural haematoma; non-acute subdural haematoma.  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 142 (2000), S. 1307-1310 
    ISSN: 0942-0940
    Keywords: Keywords: Spontaneous subdural haematoma; chronic subdural haematoma; subacute subdural haematoma; non-acute subdural haematoma.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Spontaneous subacute and chronic haematoma in young adults is rare. It has not been previously reported in this age group.  We present three cases of chronic and subacute subdural haematoma in young adults, in one of whom the diagnosis was certainly delayed.  All three patients underwent burrhole evacuation and made a full neurological recovery. A cause for the haematoma was never established. The literature on the subject, which is scanty, is reviewed and the condition is briefly discussed. The aetiology remains obscure.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1572-8773
    Keywords: Heme synthesis ; Iron metabolism ; Membranes ; Cation inhibition ; Metalloporphyrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Ferrochelatase in membrane preparations fromAzospirillum brasilense displayed an activity of 2.17 μmol protoheme formed · h−1 · mg protein−1 which is 10-fold greater than previous reports for other bacteria. This ferrochelatase showed an apparentK m of 20.9 μM for Fe2+, a pH optimum of 6.0–6.5, and stimulation by oleic or stearic acids. Co2+, Cu2+ and Zn2+ inhibited the incorporation of Fe2+ into protoporphyrin IX while Ni2 and Mg2+ had no effect on protoheme synthesis. Activity with Fe2+ and mesoporphyrin IX was less than with protoporphyrin IX but deuteroporphyrin IX produced the highest rate of protoheme synthesis. The membrane fraction containing ferrochelatase activity was found to insert Cu2+, Ni2+, Zn2+ and Co2+ enzymatically into protoporphyrin IX to produce metalloporphyrins. Cu2+ incorporation into protoporphyrin IX proceeded at a rate greater than with Fe2+ and theK m for Cu2+ was 21.9 μM.
    Type of Medium: Electronic Resource
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