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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 9 (1999), S. 192-200 
    ISSN: 1432-1084
    Keywords: Key words: Sarcoma ; Metastasis ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Both the prognosis and the morbidity of a patient with a primary malignant musculoskeletal tumour have improved over the past 25 years due to the advent of adjuvant chemotherapy and limb-sparing surgery. This has important implications for the role of imaging at the time of initial diagnosis and during follow-up. This pictorial essay reviews the imaging and pitfalls in the interpretation of musculoskeletal sarcoma metastases using a variety of radiological techniques. The optimal imaging strategy will be stressed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 7 (1997), S. 1446-1448 
    ISSN: 1432-1084
    Keywords: Key words: Osteosarcoma ; Bone scintigraphy ; MRI ; Skip metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The accurate pre-operative evaluation of the intramedullary extent of osteosarcoma is essential, as it determines the level of bone resection. Radiographs, isotope bone and MR imaging scans have been considered as reliable in detecting skeletal metastasis and skip lesions. We report a case of osteosarcoma of the distal femur with a large skip lesion proximally which was not visualized by either routine radiography or bone scintigraphy, and was not included within the scan field on the initial MR imaging scan. The implications on patient management and possible reasons for failure of imaging to reveal the skip metastasis are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 8 (1998), S. 791-799 
    ISSN: 1432-1084
    Keywords: Key words: Recurrent sarcoma ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The prognosis for a patient with a musculoskeletal sarcoma has improved considerably over the past two decades largely due to the use of adjuvant chemotherapy. Surgical techniques have become more sophisticated with limb salvage, the preferred management in the majority of cases. Imaging plays an important role in the assessment of suspected local recurrence of tumor. This pictorial essay reviews the different imaging options and highlights various pitfalls in the detection and diagnosis of recurrence. The role of magnetic resonance imaging in this respect is stressed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Skeletal radiology 28 (1999), S. 111-115 
    ISSN: 1432-2161
    Keywords: Key words Bone neoplasms ; Osteosarcoma ; Parosteal osteosarcoma ; Metatarsal ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A 70-year-old man presented with increasing swelling of 2 years’ duration, on the dorsal aspect of the forefoot. Imaging studies revealed a heavily calcified surface lesion of bone with early invasion of the underlying second metatarsal. Both imaging findings and the subsequent resection histology were consistent with a parosteal osteosarcoma, which is particularly rare at this site and at this age. The differential diagnosis of a mineralizing surface lesion of bone arising in the foot is discussed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Skeletal radiology 26 (1997), S. 667-670 
    ISSN: 1432-2161
    Keywords: Key words Intraosseous ganglia ; Juxta-articular bone cysts ; Fluid-fluid levels ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A case of an intraosseous ganglion with a fluid-fluid level visualised on MR imaging is presented. We discuss its possible pathogenesis and review other lesions that may exhibit this sign.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2161
    Keywords: Key words Clear cell sarcoma ; Malignant melanoma of soft parts ; MRI ; Magnetic resonance ; Neoplasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Objective. To evaluate MR imaging and pathology findings in order to define the characteristic features of clear cell sarcoma of the soft tissues (malignant melanoma of the soft parts). Design and patients. MR examinations of 21 patients with histologically proven clear cell sarcoma of the musculoskeletal system were retrospectively reviewed and assessed for shape, homogeneity, delineation, signal intensities on T1- and T2-weighted images, contrast enhancement, relationship with adjacent fascia or tendon, secondary bone involvement, and intratumoral necrosis. In 19 cases the pathology findings were available for review and for a comparative MR-pathology study. Results. On T1-weighted images, lesions were isointense (n=3), hypointense (n=7) or slightly hyperintense to muscle (n=11). Immunohistochemical examination was performed in 17 patients. All 17 specimens showed positivity for HMB-45 antibody. In nine of 11 lesions with slightly increased signal intensity on T1-weighted images, a correlative MR imaging-pathology study was possible. All nine were positive to HMB-45 antibody. Conclusions. Clear cell sarcoma of the musculoskeletal system often has a benign-looking appearance on MR images. In up to 52% of patients, this lesion with melanocytic differentiation has slightly increased signal intensity on T1-weighted images compared with muscle. As the presence of this relative higher signal intensity on T1-weighted images is rather specific for tumors displaying melanocytic differentiation, radiologists should familiarize themselves with this rare entity and include it in their differential diagnosis when confronted with a well-defined, homogeneous, strongly enhancing mass with slightly higher signal intensity compared with muscle on native T1-weighted images.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 18 (1994), S. 163-188 
    ISSN: 0271-2091
    Keywords: Non-linear interaction ; Hydrodynamic ; Spectral ; Finite difference ; Tidal current ; Wind-driven current ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A single-point model in the vertical is used to examine the coupling between tidal currents and wind-driven flows in shallow near-coastal regions. Calculations using both a linear slip and a no-slip condition at the sea bed clearly show that coupling between tidal and wind-driven currents cannot occur in a linear model with a time-independent eddy viscosity. However with a physically more realistic time-varying viscosity related to the flow field, coupling does occur, the magnitude of this non-linear interaction depending upon the change in eddy viscosity over a tidal cycle and the intensity of shear in the vertical. A point model in the vertical with flow induced by an oscillatory pressure gradient and an additional constant wind stress is used to examine the influence of viscosity parametrization and water depth upon this coupling.The solution in the vertical is accomplished using both a functional approach and a finite difference method. Some conclusions as to the relative merits of these approaches, particularly the use of a transformed grid in the case of high-shear surface and bed boundary layers, are made in the paper.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 3 (1983), S. 33-60 
    ISSN: 0271-2091
    Keywords: Vertical ; Eddy ; Viscosity ; Galerkin ; Method ; Hydrodynamic ; Model ; Eigenfunction ; Currents ; Roughness length ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The three dimensional linear hydrodynamic equations which describe wind induced flow in a sea are solved using the Galerkin method. A basis set of eigenfunctions is used in the calculation. These eigenfunctions are determined numerically using an expansion of B-splines.Using the Galerkin method the problem of wind induced flow in a rectangular basin is examined in detail. A no-slip bottom boundary condition with a vertically varying eddy viscosity distribution is employed in the calculation. With a low (of order 1 cm2/s) value of viscosity at the sea bed there is high current shear in this region. Viscosities of the order of 1 cm2/s) value of viscosity at the sea bed there is high current shear in this region. Viscosities of the order of 1 cm2/s near the sea bed together with high current shear in this region are physically realistic and have been observed in the sea.In order to accurately compute the eigenfunctions associated with large (of order 2000 cm2/s at the sea surface to 1 cm2/s at the sea bed) vertical variation of viscosity, an expansion of the order of thirty-five B-splines has to be used. The spline functions are distributed through the vertical so as to give the maximum resolution in the high shear region near the sea bed.Calculations show that in the case of a no-slip bottom boundary condition, with an associated region of high current shear near the sea bed, the Galerkin method with a basis set of the order of ten eigenfunctions (a Galerkin-eigenfunction method) yields an accurate solution of the hydrodynamic equations. However, solving the same problem using the Galerkin method with a basis set of B-splines, requires an expansion of the order of thirty-five spline functions in order to obtain the same accuracy.Comparisons of current profiles and time series of sea surface elevation computed using a model with a slip bottom boundary condition and a model with a no-slip boundary condition have been made. These comparisions show that consistent solutions are obtained from the two models when a physically relistic coefficient of bottom friction is used in the slip model, and a physically realistic bottom roughness length and thickness of the bottom boundary layer are employed in the no-slip model.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 12 (1991), S. 17-41 
    ISSN: 0271-2091
    Keywords: Finite difference ; Hydrodynamic ; Turbulence energy ; Tidal ; Wind wave ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper deals with the numerical solution, using finite difference methods, of the hydrodynamic and turbulence energy equations which describe wind wave and tidally induced flow.Calculations are performed using staggered and non-staggered finite difference grids in the vertical, with various time discretizations of the production and dissipation terms in the turbulence energy equations. It is shown that the time discretization of these terms can significantly influence the stability of the solution. The effect of time filtering on the numerical stability of the solution is also considered. The form of the mixing length is shown to significantly influence the bed stress in wind wave problems.A no-slip condition is applied at the sea bed, and the associated high-shear bottom boundary layer is resolved by transforming the equations onto a logarithmic or log-linear co-ordinate system before applying the finite difference scheme.A computationally economic method is developed which remains stable even when a very fine vertical grid (over 200 points) is used with a time step of up to 30 min.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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