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  • Magnetic resonance imaging  (5)
  • Analytical Chemistry and Spectroscopy  (2)
  • 1
    Electronic Resource
    Electronic Resource
    MRI of anterior spinal artery syndrome of the cervical spinal cord (1992)
    Springer
    Neuroradiology 35 (1992), S. 25-29 
    Details
    ISSN: 1432-1920
    Keywords: Anterior spinal artery syndrome ; Cervical spinal cord ; Infarct ; Magnetic resonance imaging ; Spinal angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cervical spinal cord lesions in the anterior spinal artery syndrome were delineated on magnetic resonance images (MRI) in four patients. The lesion was always seen anteriorly in the cervical cord. On T2-weighted images, the lesions appeared hyperintense relative to the normal spinal cord, while on T1-weighted images, two chronic lesions appeared hypointense, with local atrophy of the cord. In one case, repeated T1-weighted images showed no signal abnormality 4 days after the ictus, but the lesion became hypointense 18 days later, when contrast enhancement was also recognized after injection of Gd-DTPA; this sequence of intensity changes was similar to that of cerebral infarction. The extent of the lesion seen MRI correlated closely with neurological findings in all cases. Although the findings may not be specific, MRI is now the modality of choice for confirming the diagnosis in patients suspected of having an anterior spinal artery syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588273
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  • 2
    Electronic Resource
    Electronic Resource
    Cranial MRI and MR angiography in Menkes' syndrome (1993)
    Springer
    Neuroradiology 35 (1993), S. 556-558 
    Details
    ISSN: 1432-1920
    Keywords: Menkes' syndrome ; Magnetic resonance imaging ; Magnetic resonance angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two boys with Menkes' syndrome who underwent cranial MRI and MR angiography (MRA). In both, CT and MRI revealed progressive cerebral atrophy with a subdural haematoma or effusion. Delayed myelination or dysmyelination of the white matter was suggested. Tortuosity of the cervical and intracranial vessels was well demonstrated by MRA, obviating more invasive conventional angiography should it be thought necessary to demonstrate the characteristic systemic vascular changes of this syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588724
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Reye's syndrome with cortical laminar necrosis: MRI (1996)
    Springer
    Neuroradiology 38 (1996), S. 269-272 
    Details
    ISSN: 1432-1920
    Keywords: Reye's syndrome ; Cortical laminar necrosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Serial MRI findings are described in two patients with Reye's syndrome, demonstrating diffuse cortical and white matter changes. In the acute stage, T2-weighted images showed subtle but definite laminar high signal and contrast-enhanced T1-weighted images laminar enhancement, along the entire cerebral cortexbilateraly. In the chronic stage, unenhanced T1-weighted images showed diffuse cortical laminar high signal. These characteristic MRI features seemed very similar to those of laminar cortical necrosis in hypoxic brain damage. MRI also displayed delayed white matter changes with cerebral atrophy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596545
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Serial imaging in MELAS (1997)
    Springer
    Neuroradiology 39 (1997), S. 427-430 
    Details
    ISSN: 1432-1920
    Keywords: Key words Mitochondrial cytopathy ; MELAS ; Computed tomography ; Magnetic resonance imaging ; Single-photon emission computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two patients with fatal mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). Single-photon emission computed tomography (SPECT) with 123I-N-isopropyl-p-iodoamphetamine was more sensitive to the lesions than CT or MRI. SPECT showed focal hyperperfusion before or during the stroke and diffuse hypoperfusion of the brain, sparing the basal ganglia in the terminal stages. These findings support the theory that metabolic disturbance in the brain causes the “stroke” in MELAS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050438
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  • 5
    Electronic Resource
    Electronic Resource
    Reye's syndrome with cortical laminar necrosis: MRI (1996)
    Springer
    Neuroradiology 38 (1996), S. 269-272 
    Details
    ISSN: 1432-1920
    Keywords: Key words Reye's syndrome ; Cortical laminar necrosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Serial MRI findings are described in two patients with Reye's syndrome, demonstrating diffuse cortical and white matter changes. In the acute stage, T2-weighted images showed subtle but definite laminar high signal and contrast-enhanced T1-weighted images laminar enhancement, along the entire cerebral cortex bilaterally. In the chronic stage, unenhanced T1-weighted images showed diffuse cortical laminar high signal. These characteristic MRI features seemed very similar to those of laminar cortical necrosis in hypoxic brain damage. MRI also displayed delayed white matter changes with cerebral atrophy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596545
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    The gas chromatographic mass spectrometric determination of trifluoroacetic acid in biological fluid. Application to halothane metabolismAbbreviations: TFAA = trifluoroacetic acid; DMF-DMA = N,N′-dimethylformamide dimethylacetal; NADPH = nicotinamide adenine dinucleotide phosphate. (1976)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 3 (1976), S. 41-44 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The methyl ester of trifluoroacetic acid was prepared by reaction with N,N′-dimethylformamide dimethylacetal and was successfully passed through a gas chromatograph. Trifluoroacetic acid was detected by the use of gas chromatography and low and high resolution gas chromatography mass spectrometry in an acidic extract of an incubation medium containing microsomes, reduced nicotinamide adenine dinucleotide phosphate, oxygen and halothane. However, trifluoroacetic acid could not be detected when nicotinamide adenine dinucleotide or oxygen was omitted from the incubation system. From these results, it was proved that halothane is oxidatively metabolized to trifluoroacetic acid by hepatic microsomes.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200030108
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Application of high-performance liquid chromatography/atmospheric pressure ionization mass spectrometry for the analysis of non-volatile compounds (1988)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 16 (1988), S. 331-334 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The combination of a high-performance liquid chromatograph and a magnetic type mass spectrometer with an atmospheric ionization source has been applied for analyses of thermolabile compounds, i.e. antibiotics, amino acids and glycosphingolipids.Chromatography was performed on a 4 mm i.d. x 150 mm column packed with 5 μm ODS at a flow rate of 1 ml min-1. The liquid chromatography/atmospheric pressure ionization (LC/API) magnetic-type mass spectrometer provides not only an abundant pseudo-molecular ion but also fragment ions which give a structural information resulting from collision-induced dissociation at the differential pumping region of the liquid chromatograph/mass spectrometer interface. The isomers of kanamycins could be differentiated from each other on the basis of their mass spectra obtained at the relatively higher drift voltage applied. LC/API mass spectra of leucine and isoleucine were very similar, but it was easy to differentiate one from another by checking the existence of the ions at m/z 43 or m/z 57 in their mass spectra. The LC/API mass spectra of glucosylceramides showed [MH]+ ions of good abundance and significant fragment ions useful for chemical characterization at a proper drift voltage setting in a controlled and reproducible manner.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200160164
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    Paper (German National Licenses)
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