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  • 1
    ISSN: 1432-0533
    Keywords: Senile plaque ; Morphology ; Familial Alzheimer's disease ; Methenamine-Bodian method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution and morphology of senile plaques (SPs) in the cerebral cortices and subcortical nuclei of six cases of familial Alzheimer's disease (AD) were examined using the Methenamine-Bodian method and compared with those of sporadic AD cases. SPs were grouped into three types according to their morphology. SP types were generally constant at each anatomical site in all of the cases. The SPs of familial cases, however, had a greater tendency to fuse together than those of sporadic cases, especially in the cingulate cortex, presubiculum and striatum. This tendency was more evident in cases with severe amyloid angiopathy. Here it appeared that a SP type corresponding to “diffuse plaques” at least in part, might be formed by transformation from another type. In the globus pallidus, all the familial cases had many compact-like plaques which appeared to be derived from “drusige Entartung” of the capillaries. Furthermore, the regional proportion of two types of SPs occuring in this nucleus varied along its anteroposterior axis. These findings may be the histological hallmarks of atypical AD rather than familial AD.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 78 (1989), S. 131-136 
    ISSN: 1432-0533
    Keywords: Senile plaque ; Alzheimer's disease ; Brain stem ; Distribution ; Morphology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The morphology, incidence and distribution of senile plaques in the brain stem were examined in 15 cases of Alzheimer's disease, using mainly the Methenamine-Bodian method. The plaques were found in all cases and were grouped into three types according to their morphology. They were not randomly scattered in the brain stem, but had a distribution common to all cases. There were numerous plaques in the periaqueductal gray, superior colliculus, fourth-ventricle floor and superior central nucleus. The plaques were also found less abundantly in the reticular formation, substantia nigra, pontine nucleus and inferior olivary nucleus. There was a tendency for certain plaque types to be associated with specific regions. In the familial cases, the plaques tended to occur even in the regions where they were rare in other cases. The capillaries with plaque-like degeneration were observed not infrequently in the brain stem. The distribution of plaques did not always coincide with that of neurofibrillary tangles.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 4 (1994), S. 421-424 
    ISSN: 1432-1084
    Keywords: Gallbladder ; Opacification ; Contrast media ; CT ; Angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A series of CT examinations 12–24 h after angiography were performed to study the incidence of gallbladder opacification. A total of 526 patients were administered four kinds of intravascular contrast media: ioxaglate, iohexol, iopamidol and diatrizoate (mean dosage 321 ml). The degree of gallbladder opacification was classified into four grades, from normal (grade 0) to severe (grade 3), that showed high-density bile measuring more than 100 HU. Gallbladder opacification was observed in 325 patients (62%). Distinct opacification of grades 2 and 3 was shown in 48% of the ioxaglate, 46% of the iohexol, 23% of the iopamidol and 22% of the diatrizoate groups. In the ioxaglate group a high incidence of gallbladder opacification was noted not only in the renal dysfunction group, but also in the normal hepatobiliary function group with normal renal function. Gallbladder opacification after angiography was not a rare phenomenon and does not imply renal dysfunction.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1084
    Keywords: Key words: Gallbladder opacification ; Angiography ; Delayed CT ; Contrast-associated nephropathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The objective of our study was to determine the correlation between gallbladder opacification by delayed CT and contrast-associated nephropathy (CAN). Delayed CT after angiography was performed in 269 patients. Gallbladder opacification was defined when the CT value in gallbladder was more than 30 HU. Positive renal dysfunction was recognized as CAN which defined as an increase in serum creatinine level 〉 0.3 mg/dl and 〉 20 % on days 1, 3, or 7. Gallbladder opacification appeared in 154 of 269 (57 %) patients and CAN in 35 (13 %) patients. Of 117 patients without gallbladder opacification, 17 CAN (14 %) were recognized, and of 152 patients with gallbladder opacification, 18 CAN (12 %) were recognized. No significant correlation existed between delayed gallbladder opacification and CAN.
    Type of Medium: Electronic Resource
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