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  • 1
    Electronic Resource
    Electronic Resource
    Progressive supranuclear palsy with Lewy bodies (1986)
    Springer
    Acta neuropathologica 71 (1986), S. 344-346 
    Details
    ISSN: 1432-0533
    Keywords: Progressive supranuclear palsy ; Lewy body ; Parkinson's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An autopsy case is reported which revealed not only clinical and neuropathological features of progressive supranuclear palsy, but also the presence of large numbers of Lewy bodies in the brain stem nuclei and cerebral cortex. This case seems to be progressive supranuclear palsy with Lewy bodies distributed as in Parkinson's disease. Such case has not been previously reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688061
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Lewy bodies are ubiquitinated (1988)
    Springer
    Acta neuropathologica 75 (1988), S. 345-353 
    Details
    ISSN: 1432-0533
    Keywords: Lewy body ; Immunocytochemistry ; Ubiquitin ; Paired helical filaments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The nature of Lewy bodies (LBs) in the brain stem and cerebral cortex in five cases of diffuse Lewy body disease and one case of Parkinson's disease with dementia were investigated immunocytochemically with various antibodies to cytoskeletal proteins, paired helical filaments (PHF) and ubiquitin. Antibodies to 200-kDa component of neurofilament, tau and PHF showed no significant reactions with most of LBs. Antibodies to high-molecular weight microtubule-associated proteins (HMWMAPs) moderately stained the periphery of a few of LBs. A monoclonal antibody to PHF (DF2) which recognizes ubiquitin, and polyclonal antibodies to ubiquitin immunostained virtually all of the typical and cortical LBs as intensely as Alzheimer's neurofibrillary tangles and senile plaque neurites: the periphery of LBs was darkly stained, whereas the central core of typical LBs and central zone of cortical LBs were less intensely stained or remained unstained. Immunoelectron microscopy of the LBs with DF2 revealed that immune reaction products were located on the filaments exclusively in the periphery of LBs, but not on those in the center. These findings suggest that both types of LBs are immunocytochemically indistinguishable despite some structural differences, and that peripherally located filaments in LBs are tagged with ubiquitin, an element required for the ATP-dependent proteolysis system in the cell. Antibodies to ubiquitin are the most useful marker of LBs ever known.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687787
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effect of polymer composition on the production of cationic multihollow polymer particles by the stepwise acid/alkali method (1999)
    Springer
    Colloid & polymer science 277 (1999), S. 589-594 
    Details
    ISSN: 1435-1536
    Keywords: Key words Hollow ; Particle ; Emulsion polymerization ; Morphology ; Swelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The effect of the polymer composition on the formation of multihollow structures formed within submicron-sized styrene–butyl acrylate–dimethylaminoethyl methacrylate terpolymer particles by the “acid/alkali method” proposed by the authors was examined. The cationic particles were produced by seeded emulsion terpolymerization with 2,2′-azobis(2-amidinopropane) hydrochloride initiator. The dimethylaminoethyl methacrylate content and the glass-transition temperature of the terpolymer greatly affected the formation of the multihollow structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050430
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of nonionic emulsifier on the production of multihollow polymer particles by the stepwise acid/alkali method (2000)
    Springer
    Colloid & polymer science 278 (2000), S. 358-363 
    Details
    ISSN: 1435-1536
    Keywords: Key words Hollow ; Particle ; Emulsion polymerization ; Morphology ; Swelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The effects of nonionic emulsifier on the formation of multihollow structures formed within sub-micron-sized polymer particles by the “acid/alkali method” proposed by the authors were examined. The original acid-swellable particles were produced by seeded emulsion terpolymerization of styrene, butyl acrylate, and dimethylaminoethyl methacrylate. The results indicate that the nonionic emulsifier had a great effect on the formation of multihollow particles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050525
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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