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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 126 (1977), S. 199-202 
    ISSN: 1432-1076
    Keywords: Zinc ; Serum ; Normal values ; Children ; Infants ; Cord blood ; Adults
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Serum zinc concentrations in subjects of different ages were estimated by neutron activation analysis to obtain reliable reference values for the diagnosis of primary or secondary zinc deficiency during childhood. In these healthy individuals a small age-dependent variation of the mean values was found. Serum zinc concentrations were lower in cord blood (mean value: 880×10−9 g/ml) and in infants (mean value: 820×10−9 g/ml) than in adults (mean value 1178×10−9 g/ml). In comparison to these values, the serum zinc concentration in a patient with secondary zinc deficiency and 4 patients with acrodermatitis enteropathica was reduced to about 25% of normal.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 125 (1977), S. 81-88 
    ISSN: 1432-1076
    Keywords: Selenium ; Glutathione peroxidase ; Normal values ; Blood ; Infants ; Children ; Milk ; Nutrition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The selenium concentration of serum is age-dependent. The median value at birth ( $$\tilde x$$ =50×10−9g/ml) amounts to half of the median value of adults ( $$\tilde x$$ =102×10−9g/ml). After a decrease in early infancy to $$\tilde x$$ =34×10−9g/ml it steadily increases to $$\tilde x$$ =58×10−9g/ml in the second half of the first year, to $$\tilde x$$ =82×10−9g/ml in 1–5 year old children, and to $$\tilde x$$ =92×10−9g/ml in school children. The activities of the selenium containing enzyme glutathione peroxidase of erythrocytes are also reduced in early infancy (x=7.2±0.36 U37/g Hb), whereas the enzyme activities of cord blood erythrocytes (x=8.72±0.76 U37/g Hb) are in the same range as those of older children or adults. The selenium content of some commercially available milk formulas for infants are lower than those of human and cow's milk.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 150 (1969), S. 316-324 
    ISSN: 1591-9528
    Keywords: Aktivierungsanalyse ; Kobalt und Calcium ; Herzinsuffizienz ; Ratten ; Activation analysis ; Cobalt and calcium ; Cardiac failure ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Gehalt an Kobalt und Calcium im Herzmuskel und in Mitochondrienfraktionen des Herzmuskels der Ratte wurde mit Hilfe der Neutronenaktivierungsanalyse bestimmt. Nach intraperitonealer Injektion von insgesamt 50–60 mg Kobaltchlorid während einer Periode von 10–12 Tagen stieg der Gehalt an Kobalt im Herzmuskel von normal 0,15 auf 10,7 μ/g. Gleichzeitig kam es zu einer Abnahme der Calciumkonzentration im Herzmuskel von normal 265 auf 148 μg/g. Der Calciumgehalt in den Mitochondrien änderte sich dagegen nicht. Die Verschiebung des Kobalt-Calcium-Quotienten unter Kobaltchloridbehandlung kann als zahlenmäßiger Ausdruck der einsetzenden Herzinsuffizienz gewertet werden.
    Notes: Summary Concentrations of cobalt and calcium in the myocardium and in myocardial mitochondria of the rat were determined using neutron activation analysis. After intraperitoneal injections of a total dose of 50–60 mg CoCl2 during a period of 10–12 days the content of cobalt in the myocardium increased from normal 0.15 to 10.7 μg/g. At the same time calcium concentrations in the myocardium decreased from normal 265 to 148 μg/g. The calcium content of the mitochondria did not change. The shift in the ratio cobalt/calcium during treatment with CoCl2 may be quantitatively related to the resulting cardiac failure.
    Type of Medium: Electronic Resource
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