ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Sortierung

Digitale Medien

Prolactin plasma levels and D2-dopamine receptor occupancy measured with IBZM-SPECT (1996)

Schlegel, S. ; Schlösser, R. ; Hiemke, C. ; [weitere]

Springer

Psychopharmacology 124 (1996), S. 285-287

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1432-2072

Schlagwort(e): 123Iodobenzamide ([123I]IBZM) ; Single photon emission computed tomography (SPECT) ; Dopamine-D2-receptor ; Prolactin

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract By the application of123([123I]IBZM), an iodine-labelled dopamine D2-receptor antagonist, brain D2 receptors in humans can be visualized with single photon emission computed tomography (SPECT). The ratio of IBZM binding to striatal regions versus binding to frontal cortex (ST/FC ratio) provided a semiquantitative measurement of D2 receptor binding in the striatum. This study investigated the relationship between receptor occupancy and plasma prolactin levels in 12 male patients treated with haloperidol, benperidol or clozapine. Prolactin levels were positively correlated with D2 receptor occupancy, reflecting at least in part a comparable dopamine receptor antagonism in different dopaminergic pathways.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02246671

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer