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  • Myocardial perfusion  (1)
  • Radiopharmaceuticals  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The placebo effect (1997)
    Springer
    European journal of nuclear medicine 24 (1997), S. 1433-1440 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Placebo ; Pain ; Radionuclide therapy ; Nuclear medicine ; Radiopharmaceuticals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The placebo effect will have a growing importance in the field of nuclear medicine as the potentials for palliative therapy with internal sources are realized. It is important for nuclear medicine physicians and their colleagues to be familiar with the role of placebo responses in clinical trials, especially when such trials involve the subjective assessment of pain. A summary of the literature on the placebo effect in pain studies is presented in which traditional values for placebo responses are contrasted with more current thinking in the field. The few published double-blind studies of pain relief after treatment with radiotherapeutic agents are summarized specifically with respect to their cited placebo response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050173
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Biodistribution of Tc-99m methoxy-isobutyl-isonitrile (MIBI) in humans (1989)
    Springer
    European journal of nuclear medicine 15 (1989), S. 597-600 
    Details
    ISSN: 1619-7089
    Keywords: Myocardial perfusion ; Tc radiopharmaceutical ; biodistribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hexakis (methoxyisobutilisonitrile) technetium(I), 99mTc-MIBI, has been proposed for myocardial perfusion studies. We have evaluated the biodistribution of this new agent in normal volunteers at rest and after stress. The biodistribution of 99mTc-MIBI is characterized by rapid blood clearance and a consequently early myocardial uptake. The initial intense hepatic activity is cleared into the gallbladder at 1 h after injection, and the best target to non target ratio is observed at 60–90 min after injection. Absorbed radiation dose calculations show that the thyroid is the critical target organ (230 mRad/mCi at rest), presumably because of 99mTc-pertechnetate generated in vivo. Our results indicate that 99mTc-MIBI is a promising tracer for myocardial perfusion imaging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256936
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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