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  • 1990-1994  (3)
  • Serratia marcescens  (2)
  • Aligator plate  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 18 (1990), S. 299-303 
    ISSN: 1434-0879
    Keywords: MS pili ; Serratia marcescens ; Renal scarring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Renal scars are thought to be the end stage of chronic pyelonephritis and one of the most important causes of renal insufficiency and renal hypertension. The role of bacterial pili was examined in scar formation after an infection of newly constructed bacterial strains using the recombinant DNA technique, which possessed either mannose resistant (MR) or mannose sensitive (MS) pili of Serratia marcescens. Strains that differed in only a single virulence factor, namely, MR or MS pili, were used in a rat model of chronic pyelonephritis. In this model, MS-piliated bacteria stimulated renal scarring more severely than non-piliated or MR-piliated bacteria.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-0879
    Keywords: Pyelonephritis ; Renal scarring ; Pathogenesis ; Serratia marcescens ; Piliation ; Superoxide dismutase ; Leukocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The role of superoxide in scar formation following renal infection caused by mannose-sensitive (MS) piliated strains of bacteria was studied in the experimental pyelonephritis model using female Sprague-Dawley rats. The MS piliated strain stimulated renal scarring to a significantly greater extent than either the non-piliated or MR-piliated strain. Modulation of leukocytes by administering cyclophosphamide to induce neutropenia and colchicine to inhibit leukocyte migration was effective in preventing renal scarring. Treatment with superoxide dismutase during the early stage of infection was also effective in preventing scar formation. Finally, the production of superoxide by rat leukocytes was significantly larger following stimulation by MS piliated than either the nonpiliated or MR piliated strains. These observations suggest that superoxide released from leukocytes plays a critical role in the development of renal scarring following a bacterial infection, especially by MS piliated strains.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0932
    Keywords: Rachis cervical ; Arthrodèse postérieure ; Instrumentation ; Arthrodèse par plaques ; Plaques “Alligator” ; Instabilité cervicale ; Cervical spine ; Posterior fusion ; Instrumentation ; Posterior fixation ; Plate fixation ; Aligator plate ; Cervical instability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We have designed a new type of clamping plate called the “Alligator plate” for posterior cervical spinal fixation and used it in some cases with cervical instability. Seventeen patients with cervical instability treated by posterior cervical fixation using Alligator plate were clinically evaluated. As a control group, 21 patients treated by a wire fixation method (cerclage) were also evaluated. Clinical results were evaluated radiographically on dynamic flexion-extension lateral radiographs with confirmation of the fusion mass on oblique-view radiographs. The results of Alligator plate fixation were excellent in 15 patients, good in one and poor in one. The results of wire fixation were excellent in 15 patients, good in three, fair in one and poor in two. A safe and simple alternative instrumentation, the Alligator plate has sufficient stability to be useful for treating instability of the lower cervical spine.
    Notes: Résumé Nous avons créé un nouveau type de plaque à machoire appelée plaque “Alligator” destinée à l'arthrodèse postérieure du rachis cervical et nous l'avons appliquée à quelques cas d'unstabilité cervicale. L'évaluation clinique a porté sur 17 cas présentant une instabilité cervicale traitée par arthrodèse postérieure à l'aide de plaques “Alligator”. L'évaluation a aussi porté sur un groupe témoin comportant 21 cas traités par la méthode du cerclage. Les résultats cliniques ont été évalués radiologiquement d'après les clichés dynamiques de profil en flexion-extension, et confirmation de la fusion osseuse sur les radios de profil. Les résultats obtenus dans le groupe traité par les plaques “Alligator” ont été excellents chez 15 patients, bons chez l'un et mauvais chez un autre. Les résultats obtenus avec le cerclage ont été excellents chez 15 patients, bons chez trois, passables chez un et mauvais chez deux. La plaque “Alligator” représente une alternative intéressante en matière d'implants cervicaux; elle est d'une stabilité suffisante et peut se montrer de ce fait utile dans le traitement de l'instabilité du rachis cervical inférieur.
    Type of Medium: Electronic Resource
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