ISSN:
1432-0584
Keywords:
Hepatitis B virus
;
Children
;
Sicklecell anemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Screening of 143 children 6 months to 12 years of age with sickle-cell anemia showed that 39.2% were HBsAg-positive as compared with 19.3% of the 161 control children of the same age group, who had Hb genotype AA (χ2=14.7383; P〈0.001). Fifty percent of the HbSS children under the age of 1 year were HBsAg-positive as opposed to 4.3% of the control group (χ2=9.1955; P〈0.001), while 28.6% of patients were HBsAg-positive at the age of 4 years compared with only 7.4% of the controls at the same age. The incidence of anti-HBc in both groups was similar. Markers of HBV infection (HBsAg + anti-HBc) were, however, on the whole higher in the patients with sickle-cell anemia [88/118 (74.6%)] than in the controls [54/88 (61.3%; P〈0.005)].
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00320435
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