ISSN:
1432-0878
Keywords:
Spleen
;
Sinus lining cells
;
Desmosomes
;
Intercellular junctions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary 13 normal and pathological human spleens were studied by electron microscopy. In four cases (1 chronic myeloid leukemia, 1 haemolytic anaemia, 1 idiopathic thrombocytopenic purpura, 1 traumatic capsular lesion) intercellular junctions between sinus lining cells were found. These included tight junctions, “close junctions”, and intermediate junctions. There were no desmosomes. Such intercellular junctions have not been observed previously in human spleens and occur only rarely. They are thus unevenly distributed. This indicates that they probably do not impede the migration of cells through the sinus wall.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00224544
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