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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 180 (1989), S. 317-323 
    ISSN: 1432-0568
    Keywords: Joint innervation ; Sympathetic ganglia ; Spinal ganglia ; Horseradish peroxidase ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The origin of sympathetic and sensory innervation of the knee joint was investigated by the intra-axonal transport method. After injection of horseradish peroxidase (HRP) or horseradish peroxidase conjugated to wheat germ agglutinin (WGA-HRP) into the knee joint unilaterally in adult rats, labelled neurons were found ipsilaterally both in sympathetic and dorsal root ganglia at the lower thoracic and lumbosacral levels. A maximum of 1500 and 1000 peroxidase-positive cells were observed in the sympathetic and dorsal root ganglia, respectively; in the former they were mainly located at the levels of L2–L4, and in the latter mainly at L3–L5. The functional implications of the above observations are discussed in relation to pain mechanisms in joints and to the earlier hypothesis that a nervous component might be involved in the pathogenesis of chronic joint inflammation.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 181 (1990), S. 577-584 
    ISSN: 1432-0568
    Keywords: Periaqueductal gray matter ; Thalamic reticular nucleus ; Axonal transport ; Lectin conjugate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Lectin-conjugated horseradish peroxidase was either injected or implanted in crystalline form in various parts of the periaqueductal gray substance in the cat. After survival times ranging between 24 and 48 h the animals were fixed, and the mesencephalon and thalamus were sectioned and processed for peroxidase histochemistry, using tetramethylbenzidine as the chromogen. Light microscopic examination of the sections revealed that there exists a prominent reciprocal connection between the ventral and lateral parts of the periaqueductal gray matter on one hand, and the reticular nucleus of the thalamus on the other. The connections are mainly ipsilateral, and involve the entire rostrocaudal extent of the thalamic reticular nucleus, but mainly the ventrolateral sector of its caudal two thirds. There is a differential labelling within the thalamic reticular nucleus.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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