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  • 1985-1989  (2)
  • Tendon  (1)
  • feeding elicitation  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Antigen-induced tenosynovitis in hypersensitized rabbits: a model for rheumatoid tenosynovitis (1988)
    Springer
    Rheumatology international 8 (1988), S. 47-53 
    Details
    ISSN: 1437-160X
    Keywords: Rabbit ; Tenosynovitis ; Antigen ; Tendon ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rabbits were first immunized and later challenged with the same antigen (bovine serum albumin, or ferritin) by injection into the tibialis anterior tendon. Inflammatory changes of the tenosynovium and epitenon included infiltration by neutrophils (early) and mononuclear cells (later) over a 6-week course of tenosynovitis. A pattern of antigen entrapment in the tendon together with immunoglobulin was shown by use of radiolabelled antigen and immunochemical staining. Half-life of antigen in the tissues averaged 5 days over the 6-week period. Changes in the epitenon included cellular necrosis, appearance of phagocytic cells, and disruption of the collagen matrix. Tissues of control animals (challenged without prior immunization) showed minimal changes and significantly less retention of antigen (P〉0.005). The model is relevant to the mechanism of tendon damage associated with antigen-driven chronic inflammation, as may be the case in rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271834
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Feeding induced by blockade of histamine H1-receptor in rat brain (1988)
    Springer
    Cellular and molecular life sciences 44 (1988), S. 216-218 
    Details
    ISSN: 1420-9071
    Keywords: Antihistamine ; H1-receptor ; feeding elicitation ; α-fluoromethylhistidine ; hypothalamic neuronal histamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Histamine antagonists were infused into the third ventricle of the cerebrum in rats. All the H1-, but none of the H2-antagonists tested, induced initial feeding during the early portion of the light phase when histamine level was highest. No periprandial drinking was observed. Ambulation increased during feeding. The effect on feeding was attenuated when brain histamine was normally low during the early portion of the dark phase, or was decreased by α-fluoromethylhistidine. Hypothalamic neuronal histamine may suppress food intake through H1-receptors, and diurnal fluctuations of food intake may mirror neuronal histamine levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01941710
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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