ISSN:
1432-2013
Keywords:
Corticosterone
;
Dexamethasone
;
Triiodothyronine
;
Thyroidadrenalectomy
;
Adrenalectomy
;
NaK-ATPase activity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The present study concerns the effect of glucocorticoids and triiodothyronine (T3) on rat salivary (Na++K+)-adenosine triphosphatase (NaK-ATPase). The results indicate that corticosterone increases submandibular gland NaK-ATPase activity with a single dose of hormone and with two daily doses on three successive days. Multiple injections of dexamethasone also increases submandibular and sublingual gland NaK-ATPase activity. The effect of glucocorticoids on salivary NaK-ATPase is selective since Mg-ATPase shows no significant differences under different steroidal states. We subsequently investigate the possibility of interaction between the effects of corticosterone and triiodothyronine on submandibular gland NaK-ATPase activity. Our studies indicate that each of these hormones increases NaK-ATPase activity in the absence of the other.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00652748
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