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  • 1
    Electronic Resource
    Electronic Resource
    DDT and its metabolites in leiomyomatous and normal human uterine tissue (1987)
    Springer
    Archives of toxicology 59 (1987), S. 453-455 
    Details
    ISSN: 1432-0738
    Keywords: DDT ; Uterine leiomyoma ; DDE ; DDD ; Gas-liquid chromatography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Residues of dichlorodiphenyltrichloroethane (DDT) and its metabolites were monitored in leiomyomatous and normal human uterine tissue by gas-liquid chromatography (GLC). The metabolites detected were: 2,2-bis-(p-chlorophenyl)-1,1-dichloroethylene (p,p′-DDE), 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1,1-trichloroethane (o,p′-DDT), 2,2-bis-(p-chlorophenyl)-1,1-dichloroethane (p,p′-DDD) and 2,2-bis-(p-chlorophenyl)-1,1,1-trichloroethane (p,p′-DDT). Total DDT ranged from 0.245 to 1.982 ppm, with a mean value of 0.845 ppm in leiomyomatous tissue. In normal human uterine tissue, total DDT ranged from 0.030 to 0.282 ppm, with a mean value of 0.103 ppm. Significantly higher levels of DDT and its metabolites in leiomyomatous tissue as compared to normal uterine tissue suggest their involvement in uterine leiomyomas. The data is discussed in the light of existing knowledge on estrogenic activity of DDT analogs and estrogeninfluenced growth of uterine leiomyomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00316214
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  • 2
    Electronic Resource
    Electronic Resource
    A Model for diffusion controlled bioavailability of crude oil components (1997)
    Springer
    Biodegradation 8 (1997), S. 287-296 
    Details
    ISSN: 1572-9729
    Keywords: asphaltene ; bioavailability ; biodegradation ; crude oil ; diffusivity ; modeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Crude oil is a complex mixture ofseveral different structural classes of compoundsincluding alkanes, aromatics, heterocyclic polarcompounds, and asphaltenes. The rate and extent ofmicrobial degradation of crude oil depends on theinteraction between the physical and biochemicalproperties of the biodegradable compounds and theirinteractions with the non-biodegradable fraction. Inthis study we have systematically altered theconcentration of non-biodegradable material in thecrude oil and analyzed its impact on transport of thebiodegradable components of crude oil to themicroorganisms. We have also developed a mathematicalmodel that explains and accounts for the dependence ofbiodegradation of crude oil through a putativebioavailability parameter. Experimental resultsindicate that as the asphaltene concentration in oilincreases, the maximum oxygen uptake in respirometersdecreases. The mathematically fitted bioavailabilityparameter of degradable components of oil alsodecreases as the asphaltene concentration increases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008293024768
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    Paper (German National Licenses)
    Fulltext
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