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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 97 (1989), S. 89-94 
    ISSN: 0942-0940
    Keywords: Tumour marker ; brain tumour ; surgery ; radiophosphorus test ; semiconductor probe ; beta-emission measurements
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a series of 60 patients 62 intraoperative measurements with the 32-P (radiophosphorus) tumour marker were performed. Using miniature semiconductor probes a reliable discrimination between normal brain and neoplastic tissue was possible in nearly all brain tumours. The best results were found in meningiomas, where even small, visually hardly discernible tumour residues within the matrix zone could be reliably detected. Only in low-grade gliomas the application of the 32-P marker was impossible due to count rates similar to or below the basic rates of normal brain. This simple to use, noninvasive method proved its usefulness in all situations where a local radical tumour removal was important.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Free hand navigation ; optical digitizer ; frameless stereotaxy ; CT- /MRI-/ image guided brain surgery ; computer aided (assisted) surgery ; CAS ; central sensorimotor region ; brain tumour ; cavernoma ; neurosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The capacity of a new optical navigation device is demonstrated by six microsurgical procedures for small subcortical lesions within the central sensorimotor strip. This small series is aimed at less invasive resection in this functionally critical region, independently of primary diagnosis and outcome. Guided by high resolution CT imaging data five brain tumours and one cavernous angioma was selectively located and most sparingly removed without additional sensorimotor deficit. In two cases improvement of a pre-operative paresis was observed immediately after surgery. Thanks to light-weight freehand pointing instruments and a ranging accuracy of +/- 1 mm, damage to functionally important brain areas and vessels was avoided by using uncommonlyoblique, e.g., transsulcal ways of access which would hardly have been possible even with guidance by conventional stereotaxy. The demanding systematic cortical stimulation of the precentral gyrus applied in three cases was only sensitive in infiltrating tumours — e.g., low grade astrocytomas — where for want of adjuvant therapy it was essential to proceed to the extreme limits of resection. In general, precise anatomical localisation by computer aided surgery (CAS) is sufficient in small central lesions which guarantees minimally invasive surgery. The potential of this new, soon commercially available optical navigation system in (neuro)surgery, quality control and teaching is discussed.
    Type of Medium: Electronic Resource
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