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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 116 (1992), S. 60-61 
    ISSN: 0942-0940
    Keywords: Blunt head trauma ; ICP ; supratentorial pressure gradient
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary After blunt head trauma simultaneous left and right hemispheric intracranial pressure (ICP) monitoring revealed a pressure gradient of about 30 mmHg persisting until the 5th day after the accident equilibrating thereafter. ICP was elevated over the radiologically more compressed hemisphere. The supratentorial space seems to allow considerable interhemispheric pressure gradients. As a consequence epidural ICP monitoring should be performed over the hemisphere with signs of greater compression.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Single-dose antibiotic prophylaxis ; fusidic acid ; neurosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In neurosurgery, the antibiotic prophylaxis of choice has not yet been determined. The ideal drug should have an appropriate antimicrobial spectrum and favourable pharmacokinetic properties. In addition it should be nontoxic and easy to apply. We therefore conducted in 90 patients a prospective, randomized, placebo-controlled, double-blind trial in clean neurosurgery at increased risk of wound infection using a single pre-operative dose of 500 mg fusidic acid. Fusidic acid is a steroid-like antibiotic with a serum half-life of about 10 hours and excellent activity against grampositive bacteria, including methicillin-resistant staphylococci. The neurosurgical infection rates for craniotomies, posterior fossa surgery and implantation of foreign bodies were 2.4% in the treatment group and 9.1% in the placebo group, respectively. This difference is statistically significant at a 95% confidence level.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 127 (1994), S. 91-98 
    ISSN: 0942-0940
    Keywords: Abscess ; basal ganglia ; thalamus ; stereotactic puncture ; drainage ; medication ; outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A review is made of the current management strategies of abscesses in basal ganglia and thalamus, based on a review of the literature and three of our own cases. Clinical picture, aetiology, diagnostic, surgical treatment and outcome are discussed. Stereotactic abscess puncture in combination with temporary drainage and rinsing of the abscess cavity in combination with systemic medication of antibiotics has become the management of choice with satisfactory results.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 142 (2000), S. 909-912 
    ISSN: 0942-0940
    Keywords: Keywords: Microdialysis; head injury; oxygen; critical care.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  We describe multiparametric monitoring in severe head trauma using a new screwing device. Our aim was to create a screw which would make the implantation of the probes and thus multiparametric monitoring easier. The new screw allows us to implant 3 probes (microdialysis, Paratrend® and an intracranial pressure device) through one burr hole. The screw has four channels, the fourth being for ventricular drainage. We monitored 13 patients with severe head trauma (GCS=3–8) for up to 7 days. Brain tissue pO2, pCO2, pH, and temperature were measured on-line with the Paratrend® 7 machine. The microdialytic parameters glucose, lactate, pyruvate and glutamate were determined semi on-line with a CMA 600 enzymatic analyser. There were no complications in any of the patients that could be ascribed to the screw.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 121 (1993), S. 12-14 
    ISSN: 0942-0940
    Keywords: Fusidic acid ; human brain tissue ; cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Penetration of fusidic acid into brain tissue in six patients and cerebrospinal fluid in seven patients was determined. Tissue samples, taken during surgery revealed drug levels at about 7% of simultaneous serum concentrations. In contrast, cerebrospinal fluid concentrations were below 1% of serum levels. Since serum- and tissue levels of fusidic acid were far above the minimal inhibitory concentration (MICs) of staphylococci and streptococci, and since it has a long serum half-life of about 10 hours, it is a promising candidate for prophylaxis in neurosurgery.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0942-0940
    Keywords: Vertebrobasilar ectasia ; microvascular decompression ; magnetic resonance imaging/MRI ; trigeminal neuralgia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Vertebrobasilar ectasia is a rare cause of typical trigeminal neualgia. In a recently published large series only thirty-one (2%) of 1404 consecutive patients with vascularly determined neuralgia were found to have Vertebrobasilar compression. We present three patients with trigeminal neuralgia caused by Vertebrobasilar ectasia, who were evaluated with high resolution magnetic resonance imaging (MRI). MRI studies provided accurate information on the anatomical location and course of the ectatic vessel in the cerebel-lopontine angle and the caused mass effect on the brainstem. With gadolinium-enhancement vascular compression of the trigeminal nerve was demonstrated clearly. Surgery confirmed compression of the fifth nerve by an ectatic and tortuous Vertebrobasilar artery in two cases. Following microvascular decompression neither patient experienced further pain. The third patient was treated with a ventriculoperitoneal shunt, as he developed occlusive hydrocephalus caused by the Vertebrobasilar dolicho-ectasia. MRI is useful in the evaluation of trigeminal neuralgia as it excludes other aetiologies such as tumour or arteriovenous malformation, but also demonstrates cranial nerve compression by ectatic vertebral arteries.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 141 (1999), S. 465-471 
    ISSN: 0942-0940
    Keywords: Keywords: Meningioma; cerebellopontine angle; premeatal; retromeatal; cerebellar signs; auditory function; facial nerve function.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Objective. Meningiomas represent the second most common type of neoplasm of the cerebellopontine angle (cpa). Their relationship to critical neural or vascular structures of the cpa is variable and they present with different signs and symptoms.  Materials and Methods. A retrosigmoid craniotomy was performed in 31 cpa-meningiomas from January 1981 to February 1997. The mean age of the 25 women (81%) and the 6 men (19%) was 53±13 years. According to their location within the posterior fossa and with special reference to the internal auditory canal (IAC), they were classified in 17 cases (55%) as retromeatal (posterior to the iac) and in 14 cases (45%) as premeatal (anterior to the iac).  Results. The retromeatal group showed a significantly larger tumour size (21±15 vs 29±20 mm) and the diagnosis was made later ($2.7±3.2 vs 1.1±0.9 years) compared to premeatally located meningiomas. Before the operation, a reduction of the facial nerve function (64% vs 0%) and hearing function (100% vs 25%) was present significantly more often in premeatal meningiomas. The clinical appearance of the retromeatal group was dominated by cerebellar symptoms (44% vs 0%). Both preoperative and postoperative impairment of facial nerve and auditory function prevailed in the premeatal group.  Conclusion. The topological classification of CPA-meningiomas according to their location anterior or posterior to the ICA is important, because the clinical presentation, the surgical strategy to be applied, and the functional outcome of critical neural structures differ between the two subtypes. Our results provide substantial evidence for the paradoxical observation that premeatal meningiomas have a significantly worse postoperative functional outcome compared to retromeatal meningiomas although premeatal meningiomas become symptomatic earlier and at smaller sizes.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0942-0940
    Keywords: Free hand navigation ; optical digitizer ; frameless stereotaxy ; CT- /MRI-/ image guided brain surgery ; computer aided (assisted) surgery ; CAS ; central sensorimotor region ; brain tumour ; cavernoma ; neurosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The capacity of a new optical navigation device is demonstrated by six microsurgical procedures for small subcortical lesions within the central sensorimotor strip. This small series is aimed at less invasive resection in this functionally critical region, independently of primary diagnosis and outcome. Guided by high resolution CT imaging data five brain tumours and one cavernous angioma was selectively located and most sparingly removed without additional sensorimotor deficit. In two cases improvement of a pre-operative paresis was observed immediately after surgery. Thanks to light-weight freehand pointing instruments and a ranging accuracy of +/- 1 mm, damage to functionally important brain areas and vessels was avoided by using uncommonlyoblique, e.g., transsulcal ways of access which would hardly have been possible even with guidance by conventional stereotaxy. The demanding systematic cortical stimulation of the precentral gyrus applied in three cases was only sensitive in infiltrating tumours — e.g., low grade astrocytomas — where for want of adjuvant therapy it was essential to proceed to the extreme limits of resection. In general, precise anatomical localisation by computer aided surgery (CAS) is sufficient in small central lesions which guarantees minimally invasive surgery. The potential of this new, soon commercially available optical navigation system in (neuro)surgery, quality control and teaching is discussed.
    Type of Medium: Electronic Resource
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