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  • 1
    Electronic Resource
    Electronic Resource
    A. The peripheral visual pathway (1973)
    Springer
    Acta neurochirurgica 28 (1973), S. 213-221 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01432233
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    291. Craniofaciale Chirurgie (1980)
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 604-604 
    Details
    ISSN: 1435-2451
    Keywords: Craniofacial anomalies ; Surgery ; Craniofaciale Mißbildungen ; Chirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine internationale, interdisziplinäre Arbeitsgruppe für Craniofaciale Chirurgie aus München, Innsbruck und Paris zeigt neuere Möglichkeiten der operativen Korrektur schwerer Gesichts-Schädel-Mißbildungen. Operationsindikation, -planung, -techniken und Ergebnisse anhand typischer Mißbildungen wie otomandibuläre Dysostose, Craniostenosen, Apert-Syndrom, M. Crouzon und Hypertelorismus werden dargestellt.
    Notes: Summary An international, interdisciplinary craniofacial surgery group of Munich, Innsbruck and Paris presents recent achievements in the operative correction of severe craniofacial anomalies. Indications, preoperative planning, operative techniques and results are shown in cases of microsomia, Binder syndrome, craniosynostosis, Apert's syndrome, Crouzon's disease, hypertelorism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01292256
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Bedeutung der Histotopochemie und des Isoenzymmusters der Lactatdehydrogenase für die Beurteilung der Dignität von Hirntumoren (1973)
    Springer
    Journal of cancer research and clinical oncology 79 (1973), S. 319-331 
    Details
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der vorliegenden Untersuchung wurde die topochemische Verteilung der Lactatdehydrogenase (LDH) sowie das elektrophoretische Verhalten ihrer Isoenzyme bei 84 Hirngliomen des Menschen und bei 12 experimentellen Gliomen der Ratte vergleichend untersucht. Enzymtopochemisch zeigen gut differenzierte Gliome (Oligodendrogliome I, Astrocytome I) eine gleichmäßig über das ganze Schnittpräparat verteilte LDH-Aktivität („enzymatische Isochromie“). Pleomorphe Gliome bzw. Glioblastome hingegen lassen eine ausgeprägte zellindividuelle enzymatische Variabilität („enzymatische Anisochromie“) erkennen. Das LDH-Isoenzymmuster glialer Tumoren weicht nicht nur von jenem des normalen Frontalhirns deutlich ab, sondern zeigt auch bei den verschiedenen Gliomtypen statistisch gesicherte Unterschiede: Bei gut differenzierten Gliomen ist das Überwiegen der anodischen LDH-Fraktionen und der hohe Gehalt an H-Monomeren, verbunden mit einem entsprechend hohen H/M-Quotienten, charakteristisch. Demgegenüber lassen pleomorphe Gliome bzw. Glioblastome eine hohe Aktivität der kathodischen LDH-Fraktionen und einen niedrigen H-Monomerenwert, welcher einen ebenso niedrigen H/M- Quotienten zur Folge hat, erkennen. Daraus resultiert, daß gezielte enzymtopochemische und isoenzymelektrophoretische Untersuchungen zur Objektivierung der Dignität neurogener Tumoren wesentlich beitragen können.
    Notes: Summary In the present study the topochemical distribution of lactate dehydrogenase (LDH) as well as the electrophoretic characteristics of their isoenzymes of 84 human brain tumors and 12 experimental rat gliomas were investigated comparatively. The enzyme topochemical results show that well differentiated gliomas (oligodendrogliomas I, astrocytomas I) are characterized by an equally distributed LDH activity (“enzymatic isochromia”) over the whole tissue section. On the other hand pleomorphic gliomas and glioblastomas are marked by a clearly perceptible individual cell enzyme variability (“enzymatic anisochromia”). With regards to the distribution of LDH isoenzymes it was found that not only does the LDH isoenzymatic pattern of glial tumors clearly differ from that of normal frontal brain, but there are besides statistically proved differences among the different types of gliomas. Well differentiated gliomas are characterized by a predominance of anodic LDH fractions and a high percentage of H-monomers associated with a corresponding high H/M ratio. In contrast to the above mentioned gliomas, in pleomorphic gliomas and glioblastomas a high activity of cathodic LDH-fractions and a low percentage of H-monomers resulting in an equally low H/M ratio could be recognized. The present enzymological findings clearly indicate that well defined enzyme topochemical and isoenzyme electrophoretical investigations can contribute to an objectification of the status of neurogenic tumors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304026
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  • 4
    Electronic Resource
    Electronic Resource
    The brain specific proteins S100 and 14.3.2 in experimental brain tumors of the rat (1971)
    Springer
    Clinical and experimental medicine 156 (1971), S. 237-242 
    Details
    ISSN: 1591-9528
    Keywords: Nervous system ; Man ; Rat ; Spontaneous and experimental tumors ; Brain specific proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Primary tumors of the nervous system in rats induced by weekly administration of 6 mg/kg N-methylnitrosourea and spontaneous human brain tumors were investigated comparatively using immunoprecipitation technique. It is shown that two proteins antigenically identical with the specific glia proteins S100 and 14.3.2 are present in spontaneous as well as in experimental gliomas and schwannomas. These results demonstrate that the model of experimental tumors of the nervous system in rats is practicable for comparative morphological and biochemical studies of tumors of glial and schwann cell origin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02047353
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    Paper (German National Licenses)
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