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The absolute stereoschemistry at C-12 in 12-hydroxylated neo-clerodane diterpenoids

Lourenco, A. ; dela Torre, M.C. ; Rodriguez, B. ; [et al.]

Amsterdam : Elsevier

Tetrahedron 48 (1992), S. 3925-3934

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ISSN: 0040-4020

Keywords: Neo-clerodane diterpenes ; absolute configuration at C-12 ; application of the CD exciton chirality method ; differences in ^1H and ^1^3C NMR spectroscopy and molecular rotations ; epimeric C-12 alcohols, acetates and benzoates ; x-ray crystallographic analysis.

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/S0040-4020(01)88472-6

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Immunohistochemical studies of complement receptor (CR1) in cases with normal sinus mucosa and chronic sinusitis (1988)

Miyaguchi, M. ; Uda, H. ; Sakai, S. ; [et al.]

Springer

European archives of oto-rhino-laryngology and head & neck 244 (1988), S. 350-354

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ISSN: 1434-4726

Keywords: Complement receptor ; Maxillary mucosa ; Peroxidase-antiperoxidase ; Avidin-biotin peroxidase ; Immunofluorescence

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The complement receptor (CR1) in the maxillary sinus mucosa of normal patients and in cases of chronic sinusitis was studied with the peroxidase-antiperoxidase, avidin-biotin peroxidase and immunofluorescent methods. CR1 was localized on the ciliary surface and in the cytoplasm of the covering epithelium in both normal controls and the cases of chronic sinusitis. CR1 tended to be denser in the mucosa of chronic sinusitis than in normal mucosa. CR1-binding capacity was also studied with the immunofluorescent method, using C3b-conjugated zymosan. Although CR1 did not bind to C3b in vivo, it was found to bind to C3b in the normal maxillary mucosa when it was treated with C3b-conjugated zymosan. CR1-binding capacity could not be detected in the mucosa from cases with chronic sinusitis, indicating that CR1 was already bound to activated C3b in these cases.