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  • Computed tomography, liver  (1)
  • JEL classification: J51, L22, L40  (1)
  • Prostaglandin synthase  (1)
  • factor analysis  (1)
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Materialart
Erscheinungszeitraum
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  • 1
    Digitale Medien
    Digitale Medien
    Hepatic echinococcosis complicated with transphrenic migration and bronchial fistula: CT demonstration (1990)
    Springer
    Abdominal imaging 15 (1990), S. 115-118 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Computed tomography, liver ; Echinococcus ; Liver, cyst
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract An unusual case of hepatic hydatidosis complicated by transphrenic migration of the hydatid cyst passing through the right hemidiaphragm, and penetrating the inferior pulmonary lobe causing a bronchial fistula, is presented. The computed tomographic (CT) study permitted the correct preoperative diagnosis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01888752
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    QSAR and conformational analysis of the antiinflammatory agent amfenac and analogues (1993)
    Springer
    Journal of computer aided molecular design 7 (1993), S. 183-198 
    Details
    ISSN: 1573-4951
    Schlagwort(e): QSAR ; Conformational analysis ; Prostaglandin synthase ; Antiinflammatory ; Amfenac
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary The new nonsteroidal antiinflammatory drug (NSAID) arylacetic amfenac (2-amino-3-benzoylphenylacetic acid) and 19 substituted derivatives were studied in order to correlate the biological activities with the structure-related parameters. The geometry of amfenac in neutral and anionic form was totally optimized, starting from standard geometries and crystallographic data, using semiempirical AM1 and MNDO quantum-mechanical methods. Conformational analysis shows the existence of a rigid structure for rotations of the acetic acid chain (α°) and the central carbonyl group (γ°) around the bonds with the phenylamine ring, whereas the carboxyl group (β°) and the phenyl ring of the benzoyl group (δ°) can rotate almost freely. Electrostatic potential maps were analyzed and showed that the electrostatic orientation effect seems to make an important contribution to the binding of the active compounds to prostaglandin synthase. An electrostatic orientation model of the binding site is proposed. The frontier orbital charge distribution was also described for each compound. On the other hand, steric, electronic and hydrophobic (log P) parameters were calculated and QSAR analysis showed that the most significant parameter for the antiinflammatory activity was the π-electron density of the HOMO orbital in the second aromatic ring. These results suggest a possible electronic charge transfer between the aromatic fragments and the receptor.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00126444
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Corporate merger, organizational form, and control of labor (2000)
    Springer
    Spanish economic review 2 (2000), S. 129-144 
    Details
    ISSN: 1435-5477
    Schlagwort(e): JEL classification: J51, L22, L40 ; Key words: Mergers, multiproduct firms, wage bargaining
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Wirtschaftswissenschaften
    Notizen: Abstract. This paper shows that, when two firms merge, the increase in the bargaining strength of the multiproduct firm arising from the merger when negotiating uniform wages with the workers is one of the reasons that account for corporate mergers. Moreover, there is a strategic variable that can be used to decrease union rents in the case of merging, namely, the organization of production decisions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/PL00011437
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Safer Sex Communication and Unsafe Sexual Behavior Among Young Men Who Have Sex with Men in California (1999)
    Springer
    Archives of sexual behavior 28 (1999), S. 335-343 
    Details
    ISSN: 1573-2800
    Schlagwort(e): HIV/AIDS ; prevention/education ; young gay and bisexual men ; factor analysis ; sexual communication
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Psychologie
    Notizen: Abstract Our objective was to investigate sexualcommunication and risk-taking behaviors among young menwho have sex with men (MSM). MSM aged 17 to 25 yearswere recruited from four areas throughout California. The construct Safer Sex Communication, assessedthrough principal-components analysis, was defined asperceived efficacy or experience in minimizing the riskof sexual HIV infection through communication with partners. In the 6 months prior to thesurvey, 35.6% of the MSM had participated in unprotectedanal intercourse (UAI). Adjusted logistic regressionanalyses found low Safer Sex Communication to be predictive of UAI. In addition, negativeattitudes toward safe sex, high perceived risk of HIVinfection, 10 or more male sex partners during theprevious 6 months, and use of cocaine in the past 6months were also independently related to UAI. SaferSex Communication skills should be an outcome ofinterventions designed to prevent HIV transmission amongyoung MSM.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1018748729070
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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