ISSN:
0947-3440
Schlagwort(e):
Aminophosphonates
;
Phosphonates
;
Amines
;
Nitro compounds
;
Peptides
;
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The synthesis of 2-(Aminophenyl)-2-hydroxyethylphosphonates rac-4a-c is based on the formation of a hydroxyl function via addition of the lithium salt of dimethyl methylphosphonate (2) to aldehydes 1a-c. The amino function in rac- 4a-c is obtained by catalytic reduction of the nitro group in 3 at low pressure. The incorporation of the aminophosphonates rac-4a-c in short peptides, enables the formation of potential bioactive materials 12-14.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jlac.199519950254
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