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  • 1970-1974  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Perinatal telencephalic leucoencephalopathy in chimpanzees (Pan troglodytes) (1973)
    Springer
    Acta neuropathologica 25 (1973), S. 307-312 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Perinatal Telencephalic Leucoencephalopathy ; Chimpanzee ; Mucopolysaccharid Deposits ; Glial Reaction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Parenchymal deposits with the histochemical characteristics of acid glycosaminoglycans were discovered in the brains of 12 chimpanzees ranging from 6 months gestational age to 17 months post partum. Similar deposits were not seen in the brains of one fetus of approximately 3 1/2 month gestational age or in the brains of three animals that were 10 or more years of age. The deposits were found primarily in thecapsula interna, lentiform nucleus, andcapsula externa. Only a few deposits were located in the thalamus. In most instances, the mucopolysaccharid deposits were surrounded by accumulations of glial cells indicating a weak to moderate glial reaction.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00691758
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Experimental herpesvirus infection of baboons (Papio cynocephalus) and African green monkeys (Cercopithecus aethiops) and recovery of virus by tissue explants (1973)
    Springer
    Archives of virology 43 (1973), S. 304-314 
    Details
    ISSN: 1432-8798
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Adult African green monkeys and young baboons were inoculated with a baboon-derived herpesvirus (0430) which is antigenically related to herpesvirus SA8. The African green monkeys were not clinically affected, but virus could be recovered from explants. In baboons, pathogenicity was inversely related to age. In intratracheally-inoculated newborns and, to a lesser extent, in intravenously-inoculated newborns, the virus produced severe disease accompanied by weight loss, anorexia, malaise, dyspnea and fever. In 2-month and 1-year-old baboons, the virus produced no clinical symptoms. In all cases, recovery of virus from explants was superior to recovery from tissue homogenates using routine methods.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01556146
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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