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  • 11
    Electronic Resource
    Electronic Resource
    Presence of DNase γ-Like Endonuclease in Nuclei of Neuronal Differentiated PC12 Cells (1998)
    Springer
    Apoptosis 3 (1998), S. 97-103 
    Details
    ISSN: 1573-675X
    Keywords: Apoptosis ; DNA fragmentation ; DNase γ ; neurogenesis ; PC12 cells ; programmed cell death
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract DNase γ, which cleaves chromosomal DNA into nucleosomal units (DNA ladder formation), has been suggested to be the critical component of apoptotic machinery. Using rat pheochromocytoma PC12 cells, which are differentiated to sympathetic neurons by nerve growth factor (NGF), we investigated whether DNase γ-like enzyme is present in neuronal cells and is involved in neuronal cell death. The nuclear auto-digestion assay for DNase catalyzing internucleosomal DNA cleavage revealed that nuclei from neuronal differentiated PC12 cells contain acidic and neutral endonucleases, while nuclei from undifferentiated PC12 cells have only acidic endonuclease. The DNA ladder formation observed in isolated nuclei from neuronal differentiated PC12 cells at neutral pH requires both Ca2+ and Mg2+, and is sensitive to Zn2+. The molecular mass of the neutral endonuclease present in neuronal differentiated PC12 cell nuclei is 32000 as determined by activity gel analysis (zymography). The properties of the neuronal endonuclease present in neuronal differentiated PC12 cell nuclei were similar to those of purified DNase γ from rat thymocytes and splenocytes. Interestingly, in neuronal differentiated PC12 cells, internucleosomal DNA fragmentation is observed following NGF deprivation, whereas undifferentiated PC12 cells fail to exhibit DNA ladder formation during cell death by serum starvation. These results suggest that the DNase γ-like endonuclease present in neuronal differentiated PC12 cell nuclei is involved in internucleosomal DNA fragmentation during apoptosis, induced by NGF deprivation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009644924530
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  • 12
    Electronic Resource
    Electronic Resource
    Case report: glomus tumour of the nasal cavity and paranasal sinuses (1998)
    Springer
    Neuroradiology 40 (1998), S. 527-529 
    Details
    ISSN: 1432-1920
    Keywords: Key words Computed tomography ; Glomus tumour ; Nasal cavity ; Sinuses ; paranasal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Glomus tumours are relatively rare in the head and neck. We present a glomus tumour of the nasal cavity and paranasal sinuses in a 55-year-old man and describe the CT appearances of this tumour and its histopathology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050640
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  • 13
    Electronic Resource
    Electronic Resource
    Ping-pong ball avalanche at a ski jump (1998)
    Springer
    Archive for history of exact sciences 1 (1998), S. 51-56 
    Details
    ISSN: 1432-0657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Natural Sciences in General
    Notes: Abstract Three dimensional granular flow experiments were carried out on a ski jump with 300,000 ping-pong balls. Since the air drag was a large effect, the flow arrived at a steady state within a short distance. The terminal velocities attained showed a remarkable increase with the number of released balls. In addition, the flow formed a distinct head and tail structure, which has often been observed in large-scale geophysical flows in nature. Similarity analysis is used to show that the experiment corresponds to a natural snow avalanche that runs for several kilometers. Video cameras positioned above the flow allowed the measurement of the location and the distance of a single ball, which finally led to the particle velocity profiles. The static pressure depression measurements in and above the flow showed the air velocity profiles and suggested the strong interaction between the balls and the surrounding fluid(air). Computer simulation of 3-dimensional, inhomogeneous two-phase flows that uses the DEM for the particles and the Reynolds-averaged Navier Stokes equations for the fluid are currently in progress.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00010911
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  • 14
    Electronic Resource
    Electronic Resource
    Measurements of powder snow avalanche- nature - (1995)
    Springer
    Surveys in geophysics 16 (1995), S. 649-660 
    Details
    ISSN: 1573-0956
    Keywords: Powder snow avalanche ; growth rate of snow cloud ; air movement ; suspension criterion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Snow cloud growth rates of powder snow avalanche were obtained with analysing the pictures recorded in Ryggfonn, Norway. Although results showed wide scattering, as far as the data obtained in runout zone are concerned, they roughly agreed with the water tank experiments by Beghin and Olagne (1991). Air movement in snow avalanche cloud was measured with an ultra-sonic anemometer in Kurobe Canyon, Japan. It showed rising current existed near the front and downward at the trail. Comparing with drifting snow threshold and particle suspension criterion, entrainment, suspension and deposition of snow particles in the snow cloud were discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00665745
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  • 15
    Electronic Resource
    Electronic Resource
    Trehalose analysis using ion exchange HPLC coupled with electrochemical detection (1997)
    Springer
    Biotechnology techniques 11 (1997), S. 269-270 
    Details
    ISSN: 1573-6784
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A method has been developed to detect trehalose in yeast extracts down to 10mM. A crude yeast extract was prepared by rapidly heating filtered cells to 95°C. Trehalose was separated using an ion exchange HPLC connected to an electrochemical detector.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018498707686
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  • 16
    Electronic Resource
    Electronic Resource
    Conidial surface ultrastructure of human-pathogenic and saprobicCladosporium species (1995)
    Springer
    Antonie van Leeuwenhoek 68 (1995), S. 51-55 
    Details
    ISSN: 1572-9699
    Keywords: Cladosporium ; conidial surface ; conidial ultrastructure ; freeze-fracturing ; pathogenic species ; rodlets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Freeze-fracturing of outer wall layers ofCladosporium conidia revealed two types of ultrastructure, coinciding with taxonomic characteristics. The outer conidial layers were essentially smooth in the human pathogenic species,C. bantianum, C. carrionii, andC. trichoides. In contrast, mosaic arrays of rodlets on conidia were observed with freeze-fracturing in the saprobic species,C. cladosporioides, C. coralloides, C. herbarum, C. sphaerospermum, andC. variabile. Conidia ofC. elatum were an exception among the saprobic species as they had smooth surfaces. The present study supports the suggestion that the human pathogenicCladosporium species should be transferred to another genus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00873292
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  • 17
    Electronic Resource
    Electronic Resource
    A new type of growth exhibited by Trimmatostroma abietis (1996)
    Springer
    Antonie van Leeuwenhoek 69 (1996), S. 211-215 
    Details
    ISSN: 1572-9699
    Keywords: Growth ; pleomorphism ; morphology ; microcolonial fungi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Trimmatostroma abietis initially grew as hyphae when grown in various media containing yeast extract or bactopeptone. It grew as segmented elements (lumbricoid elements) characterized by bidirectional growth, when grown in Czapek-Dox broth or yeast nitrogen base supplemented with 1% glucose. A lumbricoid element usually was 10–70 μm in length, with transverse septation only and contained 3 to 15 cells. Growth and propagation, as revealed by time-lapse photomicrography occurred as follows. Elements usually grew by apical elongation without widening; after simple apical elongation adjacent parts of two central cells eventually started to grow, resulting in the separation of the element into two.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399608
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  • 18
    Electronic Resource
    Electronic Resource
    Mitochondrial DNA analysis ofExophiala spinifera (1995)
    Springer
    Mycopathologia 131 (1995), S. 67-70 
    Details
    ISSN: 1573-0832
    Keywords: Exophiala spinifera ; Mitochondrial DNA ; Restriction fragment length polymorphism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) was examined in 36 isolates ofExophiala spinifera (8 isolates from Brazil, 9 from China, 15 from Columbia, 1 from the United States and 2 from Venezuela).E. spinifera isolates displayed a high degree of mtDNA diversity in RFLP patterns and were clustered into six genetically heterogeneous groups (Group 1 through Group 6). Isolates of Group 2 including the type strain seemed to have a worldwide distribution. RFLP patterns ofE. spinifera were also distinct from those of other dematiaceous fungi, such asE. jeanselmei, E. moniliae, E. dermatitidis, Fonsecaea pedrosoi, Cladosporium carrionii andPhialophora verrucosa. These results indicate thatE. spinifera may be a taxonomic complex and that RFLP patterns will be useful in the identification, typing and epidemiology of theE. spinifera variants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01102880
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  • 19
    Electronic Resource
    Electronic Resource
    Nonlinear dynamics in the Cournot modelwithout full information (1999)
    Springer
    Annals of operations research 89 (1999), S. 165-173 
    Details
    ISSN: 1572-9338
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract A Cournot model with an arbitrary nonlinear demand function and where firms do notobserve their rival's actions directly is shown to allow mistaken beliefs to persist. Thesealter the original equilibrium state and, in a range of beliefs, destroy its stability and createcycles. The dynamics of the Cournot model are therefore fundamentally affected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018919522127
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  • 20
    Electronic Resource
    Electronic Resource
    Markov Perfect Equilibria for a classof capital accumulation games (1999)
    Springer
    Annals of operations research 89 (1999), S. 215-230 
    Details
    ISSN: 1572-9338
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract We formulate a class of dynamic games which consists of so‐called capital accumulationgames. In such games, rival firms invest strategically in a stock of physical capital. Thecapital stocks of all firms in the industry are the state variables of the game and firms usethe rate of change of the capital stocks as their control variables. It is assumed that currentprofits of a firm are not only dependent on the firm's own capital stock, but also on thestock of capital of the rival firm. We prove existence of multiple Markov Perfect Equilibria(MPE) and study their qualitative characteristics. It turns out that there exist two differenttypes of equilibria: a strict equilibrium that is degenerate and coincides with the uniqueopen‐loop one and so‐called indifferent equilibria that are non‐strict. For both types, westudy the equilibrium dynamics. While the strict equilibrium is characterized by simpleequilibrium dynamics, the indifferent equilibria may exhibit complex dynamic behaviour.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018927723944
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