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  • 11
    Electronic Resource
    Electronic Resource
    DIFFUSE THINNING OF HAIR IN IODIDE-INDUCED HYPOTHYROIDISM (1967)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 79 (1967), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1967.tb11464.x
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  • 12
    Electronic Resource
    Electronic Resource
    MYOSITIS AND MYOTONIA IN A CASE OF MULTICENTRIC RETICULOHISTIOCYTOSIS (1968)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 80 (1968), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY. A case of multicentric reticulohistiocytosis in a young man is presented, associated with a polymyositis in which myotonia was prominent. Both skin nodules and muscle abnormalities reverted to normal with steroid therapy. The cytoplasm of the giant cells in the skin nodules has been shown to contain a glycolipid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1968.tb11904.x
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  • 13
    Electronic Resource
    Electronic Resource
    A system model for the ultrasonic inspection of smooth planar cracks (1990)
    Springer
    Journal of nondestructive evaluation 9 (1990), S. 197-210 
    Details
    ISSN: 1573-4862
    Keywords: Ultrasonic inspections ; theoretical modeling ; elastodynamic ; geometrical theory of diffraction ; Kirchhoff theory ; probe ; computer codes ; experimental validation ; defect detection ; power station plant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Mathematics
    Notes: Abstract This paper describes a system model for the ultrasonic inspection of smooth planar cracks in ferritic steel, using pulse-echo probes. The model predicts the echo amplitudes and ranges as functions of the probe position. It is applied to problems of procedure design, assessment, and technical justification on power station plant. The model is implemented as a suite of versatile and user-friendly computer codes, suitable for use by practical NDT engineers, and is supported by a comprehensive user manual. The paper describes the principles of the model and gives examples of its application to power plant problems. Illustrations are also given of the extensive validation which the model has undergone through comparison with experiment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00566394
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  • 14
    Electronic Resource
    Electronic Resource
    Demonstration of Strain-hardening of Steel (1915)
    [s.l.] : Nature Publishing Group
    Nature 94 (1915), S. 589-589 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE accompanying photograph (Fig. 1) represents the side of a steel bar. The bar was first marked by a punch in the way shown, and the punch marks were afterwards completely filed out. The side was then polished and the bar pulled in a testing machine beyond the elastic limit of the material. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/094589c0
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  • 15
    Electronic Resource
    Electronic Resource
    Interactions between two neurons in contact chemosensilla of the grasshopper, Schistocerca americana (1990)
    Springer
    Journal of comparative physiology 167 (1990), S. 431-436 
    Details
    ISSN: 1432-1351
    Keywords: Contact chemosensilla ; Grasshopper ; Inhibition ; Nicotine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The tibial contact chemosensilla of Schistocerca americana contain several neurons, one of which responds to nicotine hydrogen tartrate and certain other compounds. The activity of this cell is sometimes briefly interrupted by the firing of a second cell in the same sensillum which usually only fires a few times in the first 500 ms of a stimulation. The evidence suggests that the nicotine-sensitive cell is directly inhibited by the activity of the second cell. Not all cells in the sensillum produce the same effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192578
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  • 16
    Electronic Resource
    Electronic Resource
    Of animals and men (1992)
    [s.l.] : Nature Publishing Group
    Nature 357 (1992), S. 187-187 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - I was surprised that Nature1 thought it necessary to make something of a conundrum of the fact that Charles Darwin was a strong supporter of physiology and recognized the need for experiment on animals. In 1875, largely in response to a vigorous antivivisection-ist campaign, the Cardwell ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/357187a0
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  • 17
    Electronic Resource
    Electronic Resource
    The effect of oximes on the dihydropyridine-sensitive Ca current of isolated guinea-pig ventricular myocytes (1993)
    Springer
    Pflügers Archiv 422 (1993), S. 325-331 
    Details
    ISSN: 1432-2013
    Keywords: Myocyte ; Voltage clamp ; Ionic currents ; Oximes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Exposure of isolated guinea-pig ventricular myocytes to the uncharged oximes 2,3 butanedionemonoxine (BDM) and norPAM (but not by the charged PAM) results in a dose-dependent reduction of the duration of the action potential. The nifedipine-sensitive Ca current is fully inhibited by BDM (IC505.8±0.4 mM) and nor PAM but is little affected by PAM. This inhibition is unaltered by the presence of BAY K 8644 but is antagonized by isoprenaline. The effect of isoprenaline is more pronounced when the solution in the patch pipette contains the non-hydrolysable analogue of adenosine 5′-triphosphate, ATPγS (the IC50 is increased to 44.0±5.2 mM). A hastening of the inactivation of the L-type Ca current persists when either 10 mM 1,2-bis(2-aminophenoxy)-ethane-N, N, N′, N-tetraacetic acid (BAPTA) or 3 mM ATPγS is present in the pipette solution or when BAY K 8644 or isoprenaline are present in the bathing fluid. These results suggest that the inhibition of the Ca current is due to the phosphatase-like activity of the oximes but differs in some respects from previous work where a reduced level of phosphorylation is achieved by the introduction of protein kinase inhibitors or protein phosphatases into the sarcoplasm in guinea-pig myocytes. These differences could be explained if Ca channel availability is regulated by at least two sites of cAMP-dependent phosphorylation with oximes able to rapidly dephosphorylate both sites, while one of these sites is not readily dephosphorylated by the endogenous phosphatases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00374287
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  • 18
    Electronic Resource
    Electronic Resource
    A novel resin-filled ion-sensitive micro-electrode suitable for intracellular measurements in isolated cardiac myocytes (1990)
    Springer
    Pflügers Archiv 416 (1990), S. 196-200 
    Details
    ISSN: 1432-2013
    Keywords: Myocyte ; Intracellular ions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A method for the manufacture of ion-sensitive micro-electrodes, which can be readily used with small single cells, is described in detail. A glass pipette with a tip size of 1 μm, essentially similar to those used as suction electrodes in whole-cell recording, when silanized and with its tip filled with a suitable ion-sensitive resin, producesan ion-sensitive electrode with fast electrical and chemical response times. These electrodes can be applied to the cell membrane of isolated myocytes and penetration achieved without cell damage, by the application of suction. For the estimation of intracellular ionic activities they can be used in conjunction with a separate conventional KCl-filled micro-electrode or a suction voltage electrode. The technique is illustrated by the measurement of intracellular Na+, Ca2+ and pH. It is possible that these electrodes can also be used to measure local changes in ionic activity in restricted areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00370242
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  • 19
    Electronic Resource
    Electronic Resource
    The immunology of primary sclerosing cholangitis (1990)
    Springer
    Springer seminars in immunopathology 12 (1990), S. 121-128 
    Details
    ISSN: 1432-2196
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion A number of recent studies have been discussed which provide strong evidence that genetic and immunological factors are important in the pathogenesis of PSC. Current evidence suggests that PSC is, like primary biliary cirrhosis, an immunologically mediated disease [8]. It seems likely that the immunological destruction of the biliary system is triggered in genetically predisposed individuals by viruses or bacteria [8]. The association with ulcerative colitis may be explained by the passage of viral or bacterial organisms across the damaged colonic epithelial barrier into the systemic circulation. Further studies are needed to confirm this attractive hypothesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192687
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  • 20
    Electronic Resource
    Electronic Resource
    Shape coexistence and strong shape changes in very neutron deficient platinum isotopes (1990)
    Springer
    The European physical journal 337 (1990), S. 283-292 
    Details
    ISSN: 1434-601X
    Keywords: 21.60.Ev ; 29.30.Kv ; 27.70.+q
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract High spin states of175, 176Pt have been populated in144Sm(35Cl,pxn) reactions at beam energies of 175–185 MeV. In-beamγ-ray spectroscopic techniques using the ESSA30 spectrometer array were adopted. Levels up to spin 26 in176Pt and tentatively up to spin 45/2 in175Pt have been identified. The data are interpreted within the framework of Cranked Shell Model calculations using the deformed Woods-Saxon potential and including monopole pairing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01289694
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