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  • 11
    Electronic Resource
    Electronic Resource
    Antagonistic effect of ketanserin on vasoconstrictor responses to serotonin in isolated canine skin artery (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 211-212 
    Details
    ISSN: 1432-069X
    Keywords: Skin artery ; Vasoconstriction ; Serotonin ; Ketanserin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00413262
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  • 12
    Electronic Resource
    Electronic Resource
    Low-temperature fabrication of silicon nitride films by ArF excimer laser irradiation (1988)
    Springer
    Applied physics 46 (1988), S. 249-253 
    Details
    ISSN: 1432-0630
    Keywords: 68.55 ; 73.60 ; 77.55
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The low-temperature fabrication of silicon nitride films by ArF excimer laser irradiation has been studied. Two fabrication methods are presented. One is photo-enhanced direct nitridation of a silicon surface with NH3 for very thin gate insulators, and the other is photo-enhanced deposition of silicon nitride films with Si2H6 and NH3 gases for stable passivation films. The ArF excimer laser irradiation dissociates the NH3 gas producing NH and NH2 radicals which proved effective in instigating the nitridation reaction. The quality of both films has been much improved and the growth temperature has been lowered by using laser irradiation. These photo-enhanced processes seem to be promising ULSI techniques because they do not depend on high temperatures and are free from possible reactor contamination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01141590
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  • 13
    Electronic Resource
    Electronic Resource
    Circadian variation of the urinary 6β-hydroxycortisol to cortisol ratio that would reflect hepatic CYP3A activity (2000)
    Springer
    European journal of clinical pharmacology 55 (2000), S. 861-865 
    Details
    ISSN: 1432-1041
    Keywords: Key words 6β-Hydroxycortisol ; Cortisol ; Circadian rhythm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objectives: Chronopharmacokinetics of drugs metabolized by cytochrome P 450 3A (CYP3A) has been reported recently; however, little is studied on intra-individual circadian variation in CYP3A activity in human. The aim of this study was to assess the intra-individual diurnal variation and day-to-day variation of the urinary 6β-hydroxycortisol to cortisol ratio, a noninvasive index of human CYP3A activity. Methods: Urine samples from ten healthy Japanese men were collected over four time intervals (0900 hours to 1300 hours, 1300 hours to 1700 hours, 1700 hours to 2100 hours and 2100 hours to 0900 hours) on days 1, 5 and 14 to verify diurnal variation, and 24-h urine was collected to study day-to-day variation over 2 weeks. Urinary 6β-hydroxycortisol and cortisol were determined by means of high-performance liquid chromatography/atmospheric pressure chemical ionization–mass spectrometry. Results: The ratio of urinary 6β-hydroxycortisol to cortisol exhibited noteworthy diurnal variation intra-individually; 2.8-fold on average. However, day-do-day intra-individual variation of the ratio was not observed over 2 weeks; the coefficient of variation was 11.9 ± 3.0%. Conclusion: The result indicates that imprudent use of random urine has a great risk of false evaluation in assessment of the 6β-hydroxycortisol to cortisol ratio and that the ratio in 24-h urine samples provides a more robust measure of the inter-individual difference of this metabolic ratio, which to a certain but not complete extent represents the CYP3A activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050708
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  • 14
    Electronic Resource
    Electronic Resource
    Biochemical study in 28 children with lactic acidosis, in relation to Leigh's encephalomyelopathy (1985)
    Springer
    European journal of pediatrics 143 (1985), S. 278-283 
    Details
    ISSN: 1432-1076
    Keywords: Lactic acidosis ; Pyruvate decarboxylase deficiency ; Subacute necrotizing encephalomyelopathy ; Cytochrome c oxidase deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An enzymatic study of cultured skin fibroblasts was made in 28 patients with lactic acidosis. In three of these patients a diagnosis of Leigh's encephalomyelopathy was established from autopsy findings. Pyruvate decarboxylase (PDC) deficiency was found in four patients. In two of them, in whom Leigh's encephalomyelopathy was proved by autopsy, PDC activity was lower than 10% of the normal. The other two living patients, who showed 22%–25% of the normal activity, had clinical symptoms and courses different from Leigh's disease. These findings suggest that the patients with severe PDC deficiency develop Leigh's disease but those with mild deficiency may not. A deficiency of cytochrome c oxidase was found in two siblings. One of them, who was diagnosed as having Leigh's encephalomyelopathy by postmortem examination, showed a reduction of cytochrome c oxidase in the liver and brain. In the other sibling, who is living, the reduction of cytochrome c oxidase was demonstrated in the cultured skin fibroblasts and biopsied muscle. In an electron-microscopic study of biopsied muscle, two patients with mitochondrial myopathy were found. Their fundamental enzymatic defects were unclear. In two patients, in whom Leigh's disease was suspected following a brain CT, the production of 14CO2 from [3-14C] pyruvate was found to be low; suggesting a reduced activity of the TCA cycle. In another 18 patients, the fundamental defect was not clear.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442301
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  • 15
    Electronic Resource
    Electronic Resource
    Congenital atresia of left coronary ostium (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 539-540 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955072
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  • 16
    Electronic Resource
    Electronic Resource
    Measurement of Benzo(a)pyrene in Sea Water and in Mussels in the Seto Inland Sea, Japan (2000)
    Springer
    Bulletin of environmental contamination and toxicology 65 (2000), S. 631-637 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s0012800170
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  • 17
    Electronic Resource
    Electronic Resource
    Intra-operative monitoring by facial electromyographic responses during microvascular decompressive surgery for hemifacial spasm (1996)
    Springer
    Acta neurochirurgica 138 (1996), S. 19-23 
    Details
    ISSN: 0942-0940
    Keywords: Hemifacial spasm ; intra-operative monitoring ; microvascular decompression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The facial electromyographic response was monitored intraoperatively in 40 patients with hemifacial spasm who were operated on by microvascular decompression of the facial nerve. All 40 patients showed an abnormal facial electromyographic response (lateral spread response) with a latency of about 10 msec after stimulation. The abnormal response resolved before decompression in 22, resolved immediately with decompression in 16, and failed to resolve in two. Of the 38 patients in whom the abnormal response disappeared during surgery, 36 were postoperatively free from hemifacial spasm and two had mild hemifacial spasm. The two patients in whom the lateral spread response did not disappear during surgery showed persistent hemifacial spasm. In conclusion. Disappearance of the lateral spread response during surgery correlated with the absence of hemifacial spasm in the early postoperative period. The prognosis of hemifacial spasm was good in cases in whom the lateral spread response disappeared. Therefore, the authors think that intra-operative facial electromyography is very useful in assessing the efficacy of microvascular decompression and in predicting the prognosis of hemifacial spasm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411718
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  • 18
    Electronic Resource
    Electronic Resource
    The MMAJ Rare Earth R&D Project (1991)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 70-72 (Jan. 1991), p. 325-336 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/20/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.70-72.325.pdf
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  • 19
    Electronic Resource
    Electronic Resource
    Preface
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part C, 37 (1991), S. v 
    Details
    ISSN: 1359-0197
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/1359-0197(91)90159-Y
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  • 20
    Electronic Resource
    Electronic Resource
    The effects of 5% carbon dioxide on the quantitative analysis of long-term pathology of the brain after surface hypothermia
    Amsterdam : Elsevier
    Cryobiology 27 (1990), S. 31-41 
    Details
    ISSN: 0011-2240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0011-2240(90)90050-E
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