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  • 21
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 237 (1999), S. 484-488 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  · Background: Advanced glaucoma typically results in damage of the temporal neuroretinal rim. As vascular factors are of pathogenic importance in the development of glaucomatous damage, the present study investigated whether regional differences in perfusion might be the reason for the preferential damage of the temporal neuroretinal rim. · Material and methods: Blood flow of the neuroretinal rim was measured with the laser Doppler flowmeter (LDF) Oculix 4000 (continuous measurement of an area of 160 µm diameter) and the Heidelberg retina flowmeter (HRF). Both instruments measure the capillary blood flow (flow), the relative velocity of erythrocytes (velocity) and the relative volume of moving erythrocytes (volume). We examined one randomly chosen eye of 55 healthy subjects without history of glaucoma aged 22–57 years (mean 30 years). Each subject was measured with the LDF and HRF, each time nasally and temporally, away from visible vessels. The intraocular pressure (IOP) was measured with the Goldmann tonometer. Heart rate and systolic and diastolic blood pressure were measured. · Results: The LDF measurements of the optic nerve head showed nasal flow of 12.4±5.6 AU and temporal flow of 9.8±3.6 AU. The HRF showed a nasal flow of 477±161 AU and a temporal flow of 368±166 AU. The volume measurements done by LDF showed nasally a value of 0.68±0.40 AU and temporally a value of 0.46±0.21 AU. The HRF volume measurements showed nasal values of 16.1±4.3 AU and temporal values of 13.0±4.0 AU. The LDF velocity values were nasally 0.22±0.05 kHz and temporally 0.26±0.05 kHz. HRF measurements showed velocity values of 1.7±0.5 kHz nasally and 1.3±0.6 kHz temporally. The differences were highly statistically significant for flow (LDF P=0.00007, HRF P=0.0005), volume (LDF P=0.00002, HRF P=0.00004) and velocity (LDF P=0.0002, HRF P=0.00004). The IOP was 12.6 mmHg. Blood pressure was 118/75 mmHg and the heart rate was 73 beats per minute. There was no correlation between age, IOP, BP and HR and the HRF/LDF measurements. · Conclusion: The measurements with two different methodologies showed a decreased blood flow of the temporal neuroretinal rim compared to the nasal side. These local differences might be one reason for the preferential damage of the temporal neuroretinal rim in advanced glaucoma.
    Type of Medium: Electronic Resource
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  • 22
    Electronic Resource
    Electronic Resource
    Springer
    The visual computer 14 (1998), S. 488-496 
    ISSN: 1432-2315
    Keywords: Key words: Texture mapping ; Procedural texture ; Texture control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Type of Medium: Electronic Resource
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  • 23
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 69 (1998), S. 335-337 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Nervenkompressionssyndrom ; Kiloh-Nevin-Syndrom ; N.-interosseus-anterior-Syndrom ; Sehnenruptur ; Key words Nerve compression syndrome ; Kiloh-Nevin syndrome ; Interosseus anterior nerve syndrome ; Tendon rupture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The differential diagnosis of the rupture of flexor pollicis longus tendon and profundus tendon to index finger to the interosseus anterior nerve syndrome can be difficult and can lead to misinterpretation of the clinical impression. Two cases are reported to demonstrate this problem. In the first case a spontaneous rupture of flexor pollicis longus was found, when first an interosseus anterior nerve syndrome was suspected. In a second case surgical exploration of flexor pollicis longus tendon and profundus tendon to index finger was done on the assumption of a rupture, that revealed intact tendons. In a second operation neurolysis of the interosseus anterior nerve was carried out with full recovery of flexion of the thumb and index finger.
    Notes: Zusammenfassung Die Differentialdiagnose einer Ruptur des M. flexor pollicis longus und M. flexor digitorum profundus II zum N.-interosseus-anterior-Syndrom kann schwierig sein und zu Fehlinterpretationen des klinischen Bild führen. Anhand von 2 Fallberichten soll dies aufgezeigt werden. Im ersten Fall fand sich bei klinischem Verdacht auf ein N.-interosseus-anterior-Syndrom eine Spontanruptur des Flexor pollicis longus rechts. In einem zweiten Fall wurde eine operative Exploration der langen Daumen- und tiefen Zeigefingerbeugesehne unter der Annahme einer Ruptur vorgenommen. Hier fanden sich intakte Sehnen. In einer zweiten Operation wurde die Neurolyse des N. interosseus anterior vorgenommen, die zu einer vollständigen Wiedererlangung der Beugefunktion in den Endgliedern des Daumen und Zeigefingers führte.
    Type of Medium: Electronic Resource
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  • 24
    Electronic Resource
    Electronic Resource
    Springer
    Der Ophthalmologe 97 (2000), S. 268-271 
    ISSN: 1433-0423
    Keywords: Schlüsselwörter Pigmentglaukom ; Iridotomie ; Iridektomie ; Iridozonularer Kontakt ; Ultraschallbiomikroskopie ; Key words Pigmentary glaucoma ; Laser iridotomy ; Iridozonular contact ; Ultrasound biomicroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To evaluate the anatomical relationships of the iris in pigmentary glaucoma before and after laser iridotomy and to evaluate the effect on intraocular pressure. Methods: Ultrasound biomicroscopy (UBM, Humphrey-Zeiss) of the anterior segment was performed in 28 eyes of 28 patients (20 male, 8 female, mean age 43 years, mean untreated IOP 24,3 mmHg) with pigmentary glaucoma before and after laser iridotomy. The slope of intraocular pressure was documented. Mean follow-up was 9 months. For statistical analysis the Wilcoxon test was used. Results: Ten out of 28 eyes showed iridozonular contact and concavity of the midperipheral iris. Laser iridotomy resulted in a significant pressure drop (P〈0.05) in these 10 eyes (24.6 mmHg to 18.3 mmHg). Eighteen eyes, however, did not show iridozonular contact and intraocular pressure did not drop sufficiently (P〉0.05; 25.1 mmHg to 23.1 mmHg) after laser iridotomy. Conclusion: The results show that iridozonular contact does not exist in every patient with pigmentary glaucoma. Therefore, it seems possible that more than one pathogenic mechanism is involved in pigmentary glaucoma. In patients with iridozonular contact, however, laser iridotomy significantly reduces intraocular pressure.
    Notes: Zusammenfassung Hintergrund: Bei Patienten mit Pigmentglaukom und Pigmentdispersionssyndrom wurde gehäuft eine Anlagerung des Irispigmentblattes an die Zonulafasern beobachtet. Dieser anatomischen Besonderheit wird eine pathogenetische Bedeutung bei der Entstehung der Pigmentfreisetzung zugesprochen. Ein Druckausgleich zwischen Vorderkammer und Hinterkammer durch eine Iridotomie oder Iridektomie soll den Zonulakontakt der Iris aufheben und somit eine Pigmentfreisetzung verhindern. Patienten und Methoden: Es wurden 28 Patienten mit Pigmentglaukom (20 Männer, 8 Frauen, Durchschnittsalter 43,4 Jahre, 25 der 28 Patienten waren myop) in eine prospektive, klinische Studie eingeschlossen. Der mittlere unbehandelte Augeninnendruck betrug 24,3 mmHg, alle Patienten wiesen glaukomatöse Gesichtsfelddefekte und glaukomatöse Papillenveränderungen auf. Es wurde eine Ultraschallbiomikroskopie (UBM, Humphrey-Heiss, 50 MHZ Schallkopf, Auflösung 50 mm) vor und nach YAG-Laser-Iridotomie unter standardisierten Bedingungen durchgeführt. Der Verlauf des Augeninnendruckes wurde dokumentiert und die mittlere Nachbeobachtungszeit beträgt 9 Monate. Die statistische Auswertung erfolgte mit dem Wilcoxon-Test. Ergebnisse: Bei 10 der 28 Patienten ließen sich ein irido-zonularer Kontakt und eine Konkavität der mittelperipheren Iris nachweisen. Bei diesen Patienten zeigte sich ein statistisch signifikanter Abfall (p〈0,05) des Augeninnendruckes von 24,6±2,1 mmHg auf 18,3±2,0 mmHg nach der Iridotomie. Der Augeninnendruck der Patienten, die keinen iridozonularen Kontakt aufwiesen, sank statistisch nicht signifikant um 8% von 23,1±2,3 mmHg auf 23,1±2,1 mmHg. Schlussfolgerung: Aus diesen Ergebnissen lässt sich ableiten, dass die Durchführung einer YAG-Laser-Iridotomie beim Pigmentglaukom nur dann sinnvoll erscheint, falls ein iridozonularer Kontakt mit der Ultraschallbiomikroskopie nachweisbar ist.
    Type of Medium: Electronic Resource
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  • 25
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 14 (1935), S. 275-276 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 26
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 19 (1931), S. 293-296 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 27
    Electronic Resource
    Electronic Resource
    Springer
    Plant cell reports 17 (1998), S. 415-421 
    ISSN: 1432-203X
    Keywords: Key words RAPD-PCR ; DNA-sequencing ; Vitis vinifera L. ; retrotransposon-like sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract When assaying for sequence heterogeneity within monomorphic RAPD-PCR products in grapevines (Vitis spp.), we observed partial digestibility of a marker with the restriction enzyme MspI. The degree of digestion varied reproducibly between different cultivars. To study this phenomenon, two of the amplification products were cloned and sequenced. They show 91.7% similarity to each other. The DNA analysed was found to possess high similarity to retrotransposons from higher plants. This element seems repetitive and dispersed throughout the genome. To our knowledge, this is the first report of retrotransposon-like elements in woody plants.
    Type of Medium: Electronic Resource
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  • 28
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract UPd2Al3 is a new heavy-fermion superconductor with a recordT c of 2 K. In addition, it shows a transition to long-range antiferromagnetic order atT N =14 K. Its Sommerfeld coefficient is reduced from γ p =210mJ/K2 mole in the paramagnetic to γ0=150mJ/K2 mole in the antiferromagnetic phase.
    Type of Medium: Electronic Resource
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  • 29
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 165 (1932), S. 365-376 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 30
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 175 (1937), S. 174-180 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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