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  • 1
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 90 (1986), S. 4167-4174 
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 50 (1988), S. 0 
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract: Inner retinal cells including dopamine (DA) cells were isolated and fractionated from the carp (Cyprinus carpio) retina by an enzyme cell dissociation and metrizamide gradient centrifugation method. When γ-aminobutyric acid (GABA) antagonists (bicuculline and picrotoxin) were added into the perfusate over such a cell fraction, they stimulated the release of [3H]DA which had been preloaded in the cell fraction. The action of GABA antagonists was dose and Ca2+ dependent. Their minimal effective concentration was very low (0.5 μM). A similar action was elicited by high K+. In the presence of excess GABA, this stimulatory action of GABA antagonists and high K+ on [3H]DA release was completely abolished. To interpret the action of GABA antagonists on DA cells, isolated cell fractions were preincubated with GABAse. After such a treatment, the stimulatory effects of GABA antagonists and high K+ on [3H]DA release were differentiated from each other; the former disappeared whereas the latter remained unchanged. The data strongly suggest that GABA inhibits the DA release from retinal DA cells and thus the GABA antagonists affect [3H]DA release from cell fractions not by a direct membrane action but by a disinhibition mechanism via GABA receptors on the DA cell bodies.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 62 (1987), S. 3656-3659 
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Boron doping into silicon has been investigated using an ArF excimer laser. Dopant atoms are obtained by pyrolysis of BF3. Two kinds of doping, the doping in BF3 ambients and the doping using adsorbed layers, have been performed. In both cases, the sheet resistance decreases with increasing the number of pulses. The surface concentration and the junction depth increase with the number of pulses. From these results, it is found that dopant atoms are supplied from only adsorbed layers of BF3 formed on the silicon surface. Moreover, the supply of dopant atoms from adsorbed layers limits the doping process.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 1793-1793 
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: The design of the next generation synchrotron radiation ring is based on a low-emittance storage ring with large numbers of zero-dispersion straight-section for insertion devices. As a candidate, the Chasman-Green lattice is likely to be the most promising to be investigated. In this paper, field gradients and edges which are not perpendicular to the optic axis are proposed to introduce the bending magnets for a low-emittance Chasman-Green lattice. The horizontal beam emittance of a large ring is generally expressed as1 (1) εx=Cqγθ3F(ψ)/Jx, where Cq=3.83×10−13 m, γ=Lorentz factor of the stored beam, θ=bending angle of a dipole magnet, F(ψ)=emittance form factor as a function of the betatron phase advance per half cell ψ, Jx=partition number of the horizontal betatron oscillation.The form factor F(ψ) depends on the lattice structure and is expressed for the symmetrical cell as (2) F(ψ)=(1/ρθ3)(1/ρθ) ∫ρθ0(γη2 +2αηη'+βη'2)ds, where H=γη2+2αηη'+βη'2 is the Courant–Snyder dispersion invariant, ρ is the magnetic radius, α, β, γ are Twiss parameters and η, η' are the dispersion function and the derivative with s the integral ranges over a bending magnet. We calculate, for examples, F(ψ) for a single lens approximation of equal focal length with ρ=25 and θ=π/32 radian. For the gradient magnet, the gradient parameter K is taken to be −0.05(1/m2) for example, where K is defined as (3) K=(1−n)/2, n=−(ρ/B)(dB/dx). The absolute value of K is restricted to be small to guarantee the damping of energy oscillation. For a nonperpendicular edge, the angle between the edge normal and the beam axis is chosen to be −0.255 radian, for example. The sign conversion is in the usual manner.2 The form factor F(ψ) is calculated as a function of Ψ for the two examples. Another factor to effect the emittance is the partition number Jx as seen in Eq. (1).Jx can be written as (4) Jx=1−Kρ2θ2/3, in the first-order calculation. A negative K has little effect to decrease the emittance in cooperation with F(ψ). The horizontal beam emittance is shown to be decreased by the reduction of the factor in two examples in cooperation with the increase of the horizontal damping partition number of the betatron oscillation.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 92 (1988), S. 4127-4134 
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 35 (1989), S. 0 
    ISSN: 1095-8649
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Cellular and molecular life sciences 42 (1986), S. 179-181 
    ISSN: 1420-9071
    Schlagwort(e): Xenopus thymus ; thymic rudiment ; lymphoid precursor cell ; cell immigration
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The origin of thymic lymphocytes was investigated, using a new reliable method to mark cells inXenopus. It was easily observed that extraneous cells immigrated into the thymic rudiment 4 days after fertilization and differentiated into a cell population identified as thymic lymphocytes in a fully developed thymus. Clearly, lymphoid precursor cells are of extrinsic origin.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Applied physics 42 (1987), S. 167-172 
    ISSN: 1432-0649
    Schlagwort(e): 82.50 ; 82.40 ; 42.60.Kg
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract A new working molecule 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)-propane-2-t (CF3)3CT, is reported for the isotope separation of tritium by TEA CO2-laser-induced multiphoton dissociation (MPD). Selective and efficient dissociation of (CF3)3CT was observed by irradiation at about 980 cm−1 where (CF3)3CH was nearly transparent. The critical fluence for dissociation of (CF3)3CT at 10R(28) 980.9 cm−1 was estimated to be as low as 4.6 J/cm2, which is the lowest of the tritiated halocarbons that we have ever reported. A detailed study was made of the pressure dependence of the dissociation rate constants for (CF3)3CT and (CF3)3CH to clarify the collisional effects in their MPD. The hydrogen isotope exchange between (CF3)3CH and HTO was found to be extremely rapid, which is advantageous in the practical laser separation cycle for tritium removal from water.
    Materialart: Digitale Medien
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  • 9
    ISSN: 1432-0533
    Schlagwort(e): Alkaline phosphatase ; Blood-brainbarrier ; Cytochemistry ; Endothelial cell ; Experimental allergic encephalomyelitis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary To investigate the functions of endothelial cell (ECs) in chronic relapsing experimental allergic encephalomyelitis (EAE), we examined ECs ultracytochemically in various stages of EAE, in conjunction with the localization of alkaline phosphatase (AP) activity. We also studied the relation between the specific localization of AP activity and pathological features at each stage. Chronic relapsing EAE was induced in strain-13 guinea pigs by inoculation with homologous myelin. Controls were inoculated with complete Freund's adjuvant. The controls showed AP activity on the luminal and abluminal surfaces of the plasmalemma, and in pinocytic vesicles and vesicular pits. The localization of AP activity in the preclinical stage of EAE was similar to that in control animals. The initial inflammatory and actively demyelinating stage with perivascular cuffs of mononuclear cells showed AP-positive reactions on the abluminal surface of the plasmalemma, and in vesicles and pits, but not on the luminal surface in many ECs. In a later stage showing relatively old plaques with perivascular accumulation of debris-containing macrophages, AP activity continued to show localization similar to that seen in the initial stage, except for the presence of AP activity on some segments of the abluminal plasmalemma. Inactive lesions with marked perivascular fibrosis showed no AP reaction products. AP activity in unaffected areas showed the same localization as that in control animals throughout the various clinical stages of EAE. These findings suggest that AP activity decreased as the inflammatory demyelination in EAE progressed. The gradual disappearance of AP activity suggests development of functional impairment of ECs.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 75 (1988), S. 370-376 
    ISSN: 1432-0533
    Schlagwort(e): 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism ; Crab-eating monkey ; Substantia nigra ; Locus ceruleus ; Mitochondrial abnormalities
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Experimental parkinsonism was induced by systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to the crab-eating monkey (Macaca fascicularis). In the acute stage, the substantia nigra showed necrotic nerve cells, extracellular release of pigment granules and histiocytic infiltration. The nerve cells underwent vacuolation of the cytoplasm with chromatin clumping of the nucleus and disintegration of the nucleolus. The striking feature was the presence of variously-shaped inclusion bodies within abnormal mitochondria which sometimes disclosed a distortion of the cristae. Golgi apparatus and endoplasmic reticulum were also dilated. In the locus ceruleus swollen nerve cells were observed with vacuolated cytoplasm and pyknotic nucleus where expanded mitochondria also contained the inclusions. Some of the inclusion bodies are probably insoluble precipitations due to inhibition of mitochondrial oxidation by a certain metabolite of MPTP. In the protracted stage the substantia nigra revealed a considerable loss of the nerve cells associated with melanophagia and astrocytic proliferation. A few surviving nerve cells showed an increased number of Golgi apparatus and rough endoplasmic reticula, and the presence of autophagosomes, dense bodies and intra-mitochondrial inclusions. These changes are interpreted as being a part of the reparative process from the cellular damage.
    Materialart: Digitale Medien
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