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  • 1
    Electronic Resource
    Electronic Resource
    Relation of allergy to HIV infection (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 2 (1993), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this retrospective study on 141 HIV-positive subjects, allergy was studied by a specific questionnaire and the Phadia-Top-Test, an in vitro screening test detecting specific IgE; both were correlated to the patient's history, clinical symptoms and the treatment used. Allergy was studied in reference to HIV-negative controls and in relation to the clinical and biological subgroups of HIV patients.The application of the x2 test demonstrated a high incidence of allergy and a specific relation to the HIV infection compared to the controls as well as in relation to the clinical stage of the infection. Atopy was not specifically related to the HIV infection despite the higher frequency found in the AIDS-IKEL group.A significant number (21%) of patients with T4 〉 300/μ1 considered immunocompetent presented clinical manifestations of AIDS-IKEL and 100% of these patients were allergic. A significant number (19%) of patients with T4 〈 300/μ1 considered immunodeficient were asymptomatic and 75% of them were allergic.Thus allergic symptoms may transiently be the only clinical manifestations in HIV infection and possibly a co-factor for the evolution of the disease due to the immunomodulatory function of the mediators, the cytokines and the proteases released during allergic reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1993.tb00033.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Relevance of urinalysis monitoring of methadone maintenance patients: a clinical–biological agreement on 41 patients (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Addiction biology 5 (2000), S. 0 
    Details
    ISSN: 1369-1600
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study evaluated the concordance of concomitant urinalysis and clinical assessments of drug abusers included in a methadone maintenance programme. The agreement between a clinical subjective score and an objective biological score, both measuring the evolution of illicit substance consumption over 12 months, was analysed. The clinical score, established by physicians and applied during patient interviews, was determined at entry into the programme and re-evaluated after 6 and 12 months. Forty-one patients were evaluated. The urinalysis score was based on regular screening of urine samples with the EMIT method. Agreement between the two scores was determined by using the kappa coefficient for each substance (opiates, benzodiazepines and cocaine) for each time-point. The calculated kappa coefficients showed poor agreement between the two scores, but could indicate the complementarity of these clinical and biological appraisals. Indeed, the urinalysis objectively detected change in drug use before the clinician. Thus, urinalysis monitoring should be considered as an additional and complementary biological procedure for patient follow-up by physicians.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1369-1600.2000.tb00196.x
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  • 3
    Electronic Resource
    Electronic Resource
    Solubility of Pyrocatechol in 1,2, 4-Xylenol (1946)
    [s.l.] : Nature Publishing Group
    Nature 157 (1946), S. 409-409 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] LOCAL deposits of lignite were worked up under the Germans by low-temperature carbonization and subsequent hydrogenation of tar by means of converted water gas. The water which formed in the course of this process was. extracted for phenols and other organic substances by means of isobutyl ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/157409b0
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