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  • 1
    Electronic Resource
    Electronic Resource
    Comparative study of four methods for the estimation of urinary pregnanediol
    Amsterdam : Elsevier
    Clinica Chimica Acta 8 (1963), S. 277-282 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(63)90168-2
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  • 2
    Electronic Resource
    Electronic Resource
    Relevance of urinalysis monitoring of methadone maintenance patients: a clinical–biological agreement on 41 patients (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Addiction biology 5 (2000), S. 0 
    Details
    ISSN: 1369-1600
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study evaluated the concordance of concomitant urinalysis and clinical assessments of drug abusers included in a methadone maintenance programme. The agreement between a clinical subjective score and an objective biological score, both measuring the evolution of illicit substance consumption over 12 months, was analysed. The clinical score, established by physicians and applied during patient interviews, was determined at entry into the programme and re-evaluated after 6 and 12 months. Forty-one patients were evaluated. The urinalysis score was based on regular screening of urine samples with the EMIT method. Agreement between the two scores was determined by using the kappa coefficient for each substance (opiates, benzodiazepines and cocaine) for each time-point. The calculated kappa coefficients showed poor agreement between the two scores, but could indicate the complementarity of these clinical and biological appraisals. Indeed, the urinalysis objectively detected change in drug use before the clinician. Thus, urinalysis monitoring should be considered as an additional and complementary biological procedure for patient follow-up by physicians.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1369-1600.2000.tb00196.x
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  • 3
    Electronic Resource
    Electronic Resource
    Esophageal motility and gastroesophageal reflux in children with chronic respiratory diseases (1988)
    Springer
    Pediatric surgery international 3 (1988), S. 400-406 
    Details
    ISSN: 1437-9813
    Keywords: Children ; Gastroesophageal reflux ; pH-metry ; Esophageal motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Children with chronic respiratory diseases may be a high-risk population for gastroesophageal reflux (GER). In order to describe GER in this population, we systematically studied 7-h pH-metry and prolonged esophageal manometry (over 45 min) in 124 children admitted for respiratory disorders without digestive symptoms. The results showed that: (1) GER varied in significance before and after meals; (2) postprandial reflux was correlated with esophageal motor activity, but preprandial reflux was not; (3) moderate refluxers had reduced lower esophageal sphincter (LES) pressure, but severe refluxers had no significative decrease in LES pressure. The use of multivariate analysis permitted us to conclude that long-term esophageal manometry and pH-metry were complementary in defining severe GER.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00173454
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  • 4
    Electronic Resource
    Electronic Resource
    Evaluation of allograft perfusion by radionuclide first-pass study in renal failure following renal transplantation (1986)
    Springer
    European journal of nuclear medicine 11 (1986), S. 463-469 
    Details
    ISSN: 1619-7089
    Keywords: Renal transplantation ; Radionuclide study ; Allograft perfusion ; Renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To assess the diagnostic value of indices measured on a first-pass curve, we performed 72 radionuclide renal first-pass studies (RFP) in 21 patients during the early weeks following renal allograft transplantation. The diagnosis was based on standard clinical and biochemical data and on fine needle aspiration biopsy (FNAB) of the transplant. Aortic and renal first-pass curves were filtered using a true low-pass filter and five different indices of renal perfusion were computed, using formulae from the literature. Statistical analysis performed on the aortic and renal indices indicated excellent reproducibility of the isotopic study. Although renal indices presented a rather large scatter, they all discriminated well between normal and rejection. Three indices have a particularly good diagnostic value. In the discrimination between rejection and Acute Tubular Necrosis (ATN), only one index gave satisfying results. The indices, however, indicate that there are probably ATN with an alternation of renal perfusion and rejection episodes where perfusion is almost intact. We conclude that radionuclide first-pass study allows accurate and reproducible quantitation of renal allograft perfusion. The measured parameters are helpful to followup the course of a post-transplantation renal failure episode and to gain more insight into renal ischemia following transplantation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252790
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  • 5
    Electronic Resource
    Electronic Resource
    Treatment of the childhood haemolytic uraemic syndrome with plasma (1988)
    Springer
    Pediatric nephrology 2 (1988), S. 279-285 
    Details
    ISSN: 1432-198X
    Keywords: Haemolytic uraemic syndrome ; Plasma infusions ; Multicentre therapeutic trial ; Renal failure ; Thrombotic microangiopathy ; Cortical necrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seventy-nine children with haemolytic uraemic syndrome (mean age 28 months) were randomly assigned either to a group receiving plasma infusions (plasma group,n=39) or to a group treated conservatively (control group,n=40). The duration of haemolysis, thrombocytopenia and anuria was similar in the two groups. Serum creatinine levels were similar in the two groups at the 1-month follow-up but were higher in the control group at 3 months (plasma group 49±14, control group 66±28 μmol/l;P〈0.02) and at 6 months (plasma group 48±13, control group 63±21 μmol/l;P〈0.005). The prevalence of proteinuria was also higher in the control group at the 6-month follow-up (plasma group 17%, control group 46%;P〈0.02). However differences were no longer significant after 1 year. Renal tissue was examined in 54 cases (plasma group,n=27; control group,n=27). Diffuse cortical necrosis was present in 7 cases in the control group but was absent in the plasma group (P〈0.02). Taking into consideration the higher serum creatinine levels, the higher prevalence of proteinuria during the first 6 months of follow-up in the control group and the presence of diffuse cortical necrosis in this group compared with the plasma group, we conclude that plasma infusions should be regarded as beneficial. Further study is needed to determine which plasma fraction is involved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00858677
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  • 6
    Electronic Resource
    Electronic Resource
    In vitro influence of theophylline on anti-IgE-induced histamine release from leucocytes and whole blood in asthmatic children (1981)
    Springer
    Inflammation research 11 (1981), S. 109-110 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two groups of asthmatic children were found with regard to the influence of theophylline on the anti-IgE-induced histamine release from whole blood. In the first group (21 children), histamine release was obtained both from whole blood and washed leucocytes and was inhibited by 10−4 M theophylline. In the second group (5 children), histamine release required the presence of plasma and was not inhibited by 10−4 M theophylline. Theophylline treatment was efficacious only in children of the first group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01991474
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  • 7
    Electronic Resource
    Electronic Resource
    Validation of the Revised Behavior Summarized Evaluation Scale (1997)
    Springer
    Journal of autism and developmental disorders 27 (1997), S. 139-153 
    Details
    ISSN: 1573-3432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract The Behavioral Summarized Evaluation scale (BSE), previously published and validated, was developed for the evaluation of the autistic behavior in developmentally disordered children. A revised version of this scale, the Revised Behavior Summarized Evaluation Scale (BSE-R) completed the 20-item BSE scale with the most relevant items extracted from a similar evaluation carried out with very young children. Thus 9 items were added to the original scale concerning nonverbal communication, emotional, and perception areas. This paper reports the reliability and validity studies of this new scale. In addition to confirming the previously published findings concerning the first version of the BSE, new items were extracted from the BSE-R content validity study. They involve fundamental functions such as intention and imitation which open new perspectives for a physiopathological approach to developmental disorders. The BSE-R is a useful tool for progressive recording of the evolution of patients both treated over long periods and included in short-term controlled therapeutic studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1025887723360
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  • 8
    Electronic Resource
    Electronic Resource
    The behavioral summarized evaluation: Validity and reliability of a scale for the assessment of autistic behaviors (1990)
    Springer
    Journal of autism and developmental disorders 20 (1990), S. 189-204 
    Details
    ISSN: 1573-3432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract The Behavioral Summarized Evaluation (BSE), is a 20-item paper- and-pencil rating scale specifically designed for the measurement of behavioral parameters which could be related to biological data in autistic children involved in educational programs, neurophysiological studies, and therapeutic trials. The development of the scale, the validity, and reliability studies are presented in this paper. The results suggest that the BSE is an acceptable tool for the assessment of autistic behaviors, easy to handle, and accessible to both professionals and paraprofessionals of the medico-educative staff. It is a useful addition to the bioclinical researcher's evaluation battery for bioclinical and therapeutic studies. However, more work is suggested to further investigate the psychometric properties of this behavior assessment instrument.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02284718
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