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  • 1
    Digitale Medien
    Digitale Medien
    Control of grip and stick in cell adhesion through lateral relationships of membrane glycoproteins (1977)
    [s.l.] : Nature Publishing Group
    Nature 267 (1977), S. 124-128 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Although cell adhesion to substrate must ultimately depend on ‘sticking’ by physical forces at the outer surface, we suggest that control is exercised through the ‘grip’ of the cytoskeleton. Our experiments indicate that grip can be relaxed by agents which release surface ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/267124a0
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  • 2
    Digitale Medien
    Digitale Medien
    SERUM GLYCOPROTEINS IN FIBROBLAST SPREADING ON GLASS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 312 (1978), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1978.tb16834.x
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  • 3
    Digitale Medien
    Digitale Medien
    Conformation and intermolecular interactions of carbohydrate chains (1977)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 6 (1977), S. 259-274 
    Details
    ISSN: 0091-7419
    Schlagwort(e): conformational analysis ; polysaccharides ; cooperative interactions ; synergistic interactions ; cooperative cation binding ; spectroscopic techniques ; circular dichroism ; nuclear magnetic resonance ; optical rotation ; Life Sciences ; Molecular Cell Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: For consideration of their conformations and interactions, carbohydrate chains can conveniently be divided into 3 classes on the basis of their covalent structure; namely periodic (a), interrupted periodic (b), and aperiodic (c) types. In aqueous solution carbohydrate chains often exist as highly disordered random coils. Under appropriate conditions, however, polysaccharides of types (a) and (b) can adopt a variety of ordered conformations. Physical methods, and in particular optical rotation, circular dichroism, and nuclear magnetic resonance, provide sensitive probes for the study of the mechanism and specificity of these disorder-order transitions in aqueous solution.Intermolecular interactions between such polysaccharide chains arise from co-operative associations of long structurally regular regions which adopt the ordered conformations. For acidic polysaccharides these cooperative associations may involve alignment of extended ribbons with cations sandwhiched between them. In other systems the interactions involve double belices which may then aggregate further, and geometric “matching” of different polysaccharide chains can also occur. These ordered, associated regions are generally terminated by deviations from structural regularity or by “kinks” which prevent complete aggregation of the molecules.The complex carbohydrate chains which occur at the periphery of animal cells have very different, aperiodic structures and although their conformations are as yet poorly understood, preliminary indications are considered.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jss.400060211
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