ISSN:
1432-0584
Keywords:
Leukemia, acute myelomonocytic
;
Abnormal marrow eosinophils
;
Chromosome 16
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A case of acute nonlymphocytic leukemia (ANLL) with abnormal marrow eosinophils is presented. Thorough morphological, cytochemical, and cytogenetic studies confirm the existence of a recently defined new cytogeneticmorphological entity: acute myelomonocytic leukemia with abnormal bone marrow eosinophils (FAB M4), chloracetate esterase- and periodic acid-Schiffpositivity of eosinophilic granules, and pericentric inversion of chromosome 16, in this case combined with trisomy 8. So far 18 such cases have been reported from a single institution. The implications of this new association on the diagnosis of acute leukemia with abnormal eosinophils are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00320396
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