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  • 1
    Electronic Resource
    Electronic Resource
    Reversal of experimental hemorrhagic shock by dimethylphenylpiperazinium (DMPP) (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 663-667 
    Details
    ISSN: 1420-9071
    Keywords: Hypovolemic shock ; hemorrhage ; dimethylphenylpiperazinium ; resuscitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In a rat model of hemorrhagic shock which caused the death of all control rats within 30 min, i.v. injection of the ganglion-stimulating drug dimethylphenylpiperazinium (DMPP) caused a dose-dependent reversal of the shock condition-without the need for reinfusion of the shed blood-starting from the dose of 4 ng/kg i.v. Shock reversal was associated with the mobilization of residual blood and improvement in blood flow, particularly at the carotid level. These results could influence our thinking on pathophysiology and first-aid management of shock.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02118314
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