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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 62 (1987), S. 3522-3534 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diode experiments on the PBFA-I pulser using a magnetically insulated ion diode are described. The insulating magnetic field is supplied by self-field due to the ion current plus the field generated by a series field coil. In the experiments described here, the diode operated at the 10-TW, 2.5-MV level with over 300 kJ going to the diode on many shots. The operation of the diode, the dielectric anode, and the proton beam focusing are described.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Nuclear Inst. and Methods in Physics Research, B 55 (1991), S. 782-784 
    ISSN: 0168-583X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron 46 (1990), S. 1235-1252 
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron 30 (1974), S. 3799-3805 
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Lung 97 (1942), S. 534-536 
    ISSN: 1432-1750
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 17 (1998), S. 470-478 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Erythromycin is frequently prescribed in Germany for acute otitis media, but well-designed clinical trials under present epidemiological conditions are lacking. Therefore, a double-blind, randomized, multicenter trial was performed to compare the clinical efficacy and safety of erythromycin estolate versus amoxicillin in children with acute otitis media and to identify the risk factors associated with clinical failure. Investigators from 19 centers throughout Germany recruited 302 children with clinical, otoscopic, and tympanometric evidence of acute otitis media. In a double-blind fashion, patients were allocated randomly to a 10-day course of erythromycin estolate at 40 mg/kg/day in two divided doses or amoxicillin at 50 mg/kg/day in two divided doses. Clinical examinations, otoscopy, and tympanometry were performed at baseline, day 3–5, day 9–11, and at 5 weeks. Clinical outcome was assessed on day 9–11. Two-hundred eighty children were evaluable for efficacy (erythromycin group, 141; amoxicillin group, 139). Both groups were comparable with respect to demographic data and severity of disease at entry. Treatment was successful in 94% of the erythromycin-treated patients and in 96% of the amoxicillin-treated patients. Clinical outcome was statistically equivalent between groups within a range of 7 percentage points. Clinical recurrence was seen in eight erythromycin-treated children (5.7%) and in seven amoxicillin-treated children (5.0%) (P=0.81). Patients with bilateral disease at entry were at higher risk of unfavourable outcome, whereas age and presence/absence of otorrhea at entry were not associated with outcome. Treatment-related adverse events were recorded in eight (5.3%) of 151 erythromycin-treated patients and in 11 (7.3%) of 151 amoxicillin-treated patients. In this study in an outpatient setting in Germany, erythromycin estolate was as safe and effective as amoxicillin in the treatment of acute otitis media. Both drugs can be administered in a convenient twice-daily dosage schedule.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 21 (1982), S. 43-50 
    ISSN: 1436-6215
    Keywords: dietary induced thermogenesis ; direct calorimetry ; postprandial core temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Es wurde die postprandiale Thermogenese von Diäten unterschiedlichen Protein- und Fettanteils an jungen männlichen wachsenden Ratten mit der direkten Kalorimetrie bestimmt. Die postprandiale Thermogenese nach Kontrolldiät, die 30% Kasein enthält, betrug 8,3% der aufgenommenen Bruttoenergie. Nach Austausch der Hälfte des Kasein durch Gelatine erhöhte sich die postprandiale Wärmeabgabe auf 19,3% der aufgenommenen Bruttoenergie. Substitution von Schmalz durch mittelkettige Triglyceride und kombinierte Substitution durch mittelkettige Triglyceride und Gelatine verursachten einen weiteren Anstieg der Thermogenese auf 20,3 % bzw. 22,6% der aufgenommenen Bruttoenergie. Verglichen mit der Kontrolldiät sind diese Differenzen statistisch hoch signifikant. Die postprandiale Thermogenese nach Kasein- und Kasein-Gelatine-haltigen Diäten tritt 2,5 Stunden nach der Nahrungsaufnahme ein und dauert 2–3 Stunden. Die Diäten, die mittelkettige Triglyceride enthalten, rufen 45–90 Minuten nach der Nahrungsaufnahme einen signifikanten Anstieg der Wärmeabgabe hervor, der 2–3 Stunden dauert. Die Kombination von Diätkomponenten mit einer hohen postprandialen Wärmeabgabe führte nicht zu einer additiven Wärmeabgabe. Es bestand eine enge Korrelation zwischen der aufgenommenen Nahrungsmenge und der postprandialen Wärmeabgabe. Die Kerntemperatur der Ratten stieg nach Nahrungsaufnahme der Versuchsdiäten signifikant an. In der postprandialen Phase wurden jedoch keine signifikanten Unterschiede zwischen den vier Versuchsgruppen gefunden. Die Ergebnisse zeigen, daß die postprandiale Wärmeabgabe durch ausgewählte Diätkomponenten signifikant gesteigert werden kann. Die Entwicklung von Diäten mit einer geringen Effizienz der Energieverwertung könnte von Interesse sein für spezielle Diätbehandlungen wie zum Beispiel der Adipositas.
    Notes: Summary The postprandial thermic effect of diets containing different protein and fat moieties was estimated in young male growing rats by direct calorimetric measurements. The postprandial thermogenesis after ingestion of the control diet, which contained 30% of casein, corresponded to 8.3% of the gross energy. After exchange of half the casein by gelatine, the postprandial heat loss increased to 19.3% of the gross energy. Substitution of lard by medium-chain triglycerides and gelatine caused a further increase of thermogenesis to 20.3% and 22.6% of gross energy, respectively. Compared to the control diet, the differences are highly statistically significant. The postprandial heat production after ingestion of the casein and caseingelatine-containing diets occurred 2.5 hours after food intake and lasted about 2–3 hours. The medium-chain triglycerides-containing diets induced 45–90 minutes after food intake a significant increase of the heat production, lasting likewise 2–3 hours. The combination of dietary components with a high postprandial thermogenetic effect did not lead to an additive heat production. A very close correlation could be found between the amount of food intake and the postprandial heat loss. The core temperature of rats increased significantly after ingestion of the experimental diets. In the postprandial state it did not differ between the four experimental groups. The results demonstrate that the postprandial heat loss can be significantly increased by selected dietary components. The development of diets with a lower efficiency of energy utilization could be of interest for special dietary treatments, as for example, in certain states of obesity.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 32 (1993), S. 71-73 
    ISSN: 1436-6215
    Keywords: Rat ; glutamate-induced obesity ; postprandial thermogenesis ; Ratte ; Glutamat-induzierte Adipositas ; postprandiale Thermogenese
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Bei 4 Monate alten Ratten mit Glutamat-induzierter Adipositas wurde die postprandiale Thermogenese über 8 h nach Fütterung von 300, 450 und 600 kJ/kg0,75 einer Pellet-Diät mittels indirekter Kalorimetrie in computergesteuerten Stoffwechselkäfigen mit offenem Kreislauf bestimmt. Bei den adipösen Tieren war die postprandiale Thermogenese nach Aufnahme von 600 kJ/kg0,75 (oberhalb des Energieerhaltungsbedarfs) signifikant auf 40% der Thermogenese der Kontrolltiere reduziert (12,0 gegenüber 31,5 kJ/kg0,75×8 h). Es wird geschlußfolgert, daß die Ratte mit Glutamat-induzierter Adipositas als ein Tiermodell mit beeinträchtigter fakultativer Thermogenese anzusehen ist, die hauptsächlich durch eine Verminderung der sympathischen adrenergen Aktivität verursacht ist.
    Notes: Summary Postprandial thermogenesis was estimated in 4-month-old male rats with glutamate induced obesity after being fed with 300, 450 and 600 kJ/kg0.75 of a pellet diet, respectively by indirect calorimetry in computer-controlled open circuit metabolic cages over 8 h. After an intake of 600 kJ/kg0.75 (above the maintenance energy requirement) postprandial thermogenesis was significantly reduced in the obese animals to about 40% of control rats (12.0 versus 31.5 kJ/kg0.75×8 h). It is concluded that the glutamate obese rat can be accepted as an animal model with impaired facultative thermogenesis, mainly caused by a reduction of sympathetic adrenergic activity.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 34 (1995), S. 32-33 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Type of Medium: Electronic Resource
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