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  • 1
    Digitale Medien
    Digitale Medien
    Phosphatidylinositol:myo-Inositol Exchange Activity in Intact Nerve Endings: Substrate and Cofactor Dependence, Nucleotide Specificity, and Effect on Synaptosomal Handling of myo-Inositol (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 46 (1986), S. 0 
    Details
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract: Micromolar concentrations of CMP produced a large increase in Mn2+ -dependent phosphatidylinositol:myo-inositol exchange activity in isolated nerve endings or synaptosomes. The apparent Km for CMP was 2 μM, and that for myo-inositol was 38 μM. Only cytidine nucleotides were capable of enhancing activity, and this effect is probably specific for CMP, because the synaptosomal preparation rapidly converted CTP or CDP to CMP. Manganese did not affect the uptake of myo-inositol into the synaptosomal cytosolic fraction or myo-inositol levels. Determinations of myo-inositol specific activity showed that the Mn2+-enhanced labeling of phosphatidylinositol was not accompanied by a decrease of label content in free myo-inositol. This lack of an effect on intrasynaptosomal myo-inositol and the dependence of exchange on cytidine nucleotides whereas cytidine itself was previously found to be without effect show that for the bulk of Mn2+-dependent exchange activity, it is the myo-inositol in the incubation medium that is being directly incorporated into membrane-bound phosphatidylinositol. Because CMP dependence is the hallmark of exchange catalyzed by CDP-diacylglycerol:inositol phosphatidyl transferase, this enzyme is likely to be responsible for most of the exchange activity in synaptosomes. The strong affinity of this exchange system for CMP suggests that endogenous levels of this nucleotide might support Mn2+-dependent exchange in the absence of added nucleotide.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-4159.1986.tb00620.x
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  • 2
    Digitale Medien
    Digitale Medien
    Maternal and perinatal morbidity of caesarean delivery at full cervical dilatation compared with caesarean delivery in the first stage of labour (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To estimate maternal and perinatal morbidity associated with caesarean delivery at full cervical dilatation, a population-based cohort study from 1997 to 2002 was used, which included 1623 nullipara with singleton pregnancies at 37–42 weeks of gestation requiring caesarean delivery in labour. Compared to caesarean delivery at less than full dilatation, women undergoing caesarean delivery at full dilatation were more likely to have complications of intraoperative trauma (RR 2.6, P 〈 0.001) and infants with perinatal asphyxia (RR 1.5, P 〈 0.05). There was no difference in maternal or perinatal morbidity when duration of the second stage of labour or when failed assisted vaginal delivery was considered.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-0528.2005.00615.x
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  • 3
    Digitale Medien
    Digitale Medien
    Transport of steroids at model biomembrane surfaces and across organic liquid-aqueous phase interfaces [Erratum to document cited in CA111(14):120701m] (1990)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 94 (1990), S. 2726-2726 
    Details
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/j100369a090
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  • 4
    Digitale Medien
    Digitale Medien
    Quantitative long-range-order measurement and disordering efficiency estimation in ion-irradiated bulk Ni3Al using cross-sectional conventional transmission electron microscopy (2000)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 77 (2000), S. 2680-2682 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Irradiation-induced disordering of bulk Ni3Al under 6 MeV Ni2+ irradiation is studied at room temperature. A self-consistent long-range-order quantification method for ion-irradiated intermetallics is presented using cross-sectional sample preparation and conventional transmission electron microscopy in selected area diffraction depth profiling mode. This method, which does not require the full assessment of dynamic diffraction image simulation information, is unique to precisely measure long-range-order as a function of depth or dose for a single total fluence. The disordering efficiency constant ε is estimated in the range 10.0±0.7/dpa for a total fluence of 1014 cm−2. © 2000 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1320037
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  • 5
    Digitale Medien
    Digitale Medien
    New insight into proton-induced latchup: Experiment and modeling (1993)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 2952-2954 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: A combination of irradiation experiments (using energetic protons and heavy ions) and a theoretical analysis was used, for the first time, to study proton induced single event latchup (SEL) in electronic devices. A significant difference between SEL and single event upset (SEU) was found. For SEU the device sensitivity can be predicted by a model assuming the collection of the majority of the charge carriers generated in the sensitive volume by the nuclear fragments of the (p,Si) reactions. For SEL, the measured sensitivities are much lower than predicted by prompt charge collection. Recombination of charge carriers (generated by the heavier fragments) due to a track electric field reasonably explains the SEL data.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.110283
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  • 6
    Digitale Medien
    Digitale Medien
    Single Versus Dual Chamber Pacing in the Young: (2003)
    350 Main Street , Malden , MA 02148-5018 , U.S.A . : Blackwell Publishing
    Pacing and clinical electrophysiology 26 (2003), S. 0 
    Details
    ISSN: 1540-8159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The advantages of atrial synchrony over asynchronous ventricular pacing remain unclear in the young, chronically right ventricular (RV) - paced patient. This is in contrast to the older patient with inherent diastolic dysfunction who has been shown to benefit from atrial synchrony with dual chamber (DDD,R/VDD), over single chamber rate response (VVI,R) ventricular pacing. The goal of this study was to noninvasively assess cardiac function in a group of young, RV-paced patients before and after establishment of atrial synchrony. Echocardiographic data were retrospectively analyzed from 10 patients with congenital or acquired complete AV block, who were VVI,R paced for 10.2 ± 2 years (mean age at study 19.2 ± 8.9 years), and were subsequently converted to DDD,R/VDD pacing (mean age at study 20.7 ± 9.5 years). Paired t-test analysis of left ventricular (LV) systolic and diastolic function during VVI,R versus DDD,R/VDD pacing did not result in any short-term difference in LV short axis fractional area of change or FAC (53%± 7.5% vs 56.8%± 8.7%) or mitral maximal velocity (E) normalized to mitral flow velocity time integral (VTI) (5.2/s ± 1.5 vs 4.4/s ± 1.5). A decrease in mitral flow E/A ratio was observed after short term DDD,R/VDD pacing (2.2 ± 0.5 vs 1.9 ± 0.3). Atrial synchronous dual chamber pacing in young patients with complete AV block does not lead to any appreciable early change in global LV function over single-site RV pacing. Therefore, early establishment of atrial synchrony in the young asymptomatic VVI,R-paced patient with normal intrinsic ventricular function may not be warranted. (PACE 2003; 26:1208–1211)
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1460-9592.2003.t01-1-00170.x
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  • 7
    Digitale Medien
    Digitale Medien
    Factitious purpura (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 17 (1992), S. 0 
    Details
    ISSN: 1365-2230
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Factitious purpura may present as a perplexing problem for the dermatologist and can mimic serious disease. This form of mechanical purpura, often caused by suction may be deliberately or unknowingly induced by the patient. Some cases may go unrecognized for a considerable length of time and undergo unnecessary investigation before the diagnosis is realized. Three cases of purpura are reported in which the causative agents were very different.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2230.1992.tb02156.x
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  • 8
    Digitale Medien
    Digitale Medien
    Reply (1983)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 109 (1983), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1983.tb00558.x
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  • 9
    Digitale Medien
    Digitale Medien
    Early diagnosis of infantile seborrhoeic dermatitis and atopic dermatitis—total and specific IgE levels (1983)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 108 (1983), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Total and antigen-specific IgE levels using the radioallergosorbent test (RAST) were measured in a prospective study of thirty-seven infants with dermatitis of early infancy, with the aim of distinguishing between atopic and infantile seborrhoeic dermatitis at an earlier age than is usually possible on clinical grounds. The results were correlated with the clinical diagnoses made after 1–2 years close follow-up. They showed that a RAST screen to egg white and to milk antibodies, and to a lesser extent total IgE levels, are of value in diagnosing atopic dermatitis at an early age and distinguishing this from infantile seborrhoeic dermatitis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1983.tb01075.x
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  • 10
    Digitale Medien
    Digitale Medien
    Early diagnosis of infantile seborrhoeic dermatitis and atopic dermatitis—clinical features (1983)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 108 (1983), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In a prospective study of thirty-seven infants presenting with dermatitis in early infancy it was found that pruritus, a positive family history of atopy, and the age of onset of skin lesions were of little value in distinguishing atopic dermatitis from infantile seborrhoeic dermatitis. The most useful distinguishing features were the increased incidence of lesions on the forearms and shins in atopic dermatitis, and in the axillae in infantile seborrhoeic dermatitis. The onset of skin lesions solely in the napkin area favoured a diagnosis of infantile seborrhoeic dermatitis, but when more than one site was involved the distinction was less clear. Infantile seborrhoeic dermatitis carried a much better prognosis than atopic dermatitis. In thirty-six out of thirty-seven infants the definitive diagnosis could be made with confidence on clinical grounds by the age of 1 year, but was often difficult at first presentation in early infancy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1983.tb01074.x
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