ZIB

Treffer pro Seite

Treffer 1 - 3 | 3 Treffer

Sortierung

Digitale Medien

Risk factors for small bowel cancer in Crohn's disease (1992)

Lashner, Bret A.

Springer

Digestive diseases and sciences 37 (1992), S. 1179-1184

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1573-2568

Schlagwort(e): small bowel cancer ; Crohn's disease ; risk factors

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirms any suspected risk factor. A mase-control study was performed to identify possible alternatives. Each case was matched to four randomly selected controls from an inflammatory bowel disease registry matched for year of birth, sex, and confirmed small bowel Crohn's disease. Three factors were significantly associated with the development of cancer: (1) Four cancers developed in the jejunum, and jejunal Crohn's disease was associated with the development of cancer [odds ratio (OR) 8.0, 95% confidence interval (CI) 1.6-39.3]. (2) There was an association between the development of cancer and occupations known to be associated with an increased colorectal cancer risk (OR 20.3, CI 2.7-150.5). Three cases (a chemist with exposure to halogenated aromatic compounds and aliphatic amines, a pipefitter with exposure to asbestos, and a machinist with exposures to cutting oils, solvents, and abrasives) and one of 28 controls (a fireman with multiple hazardous exposures) had an occupational risk factor. (3) Among medications taken for at least six months only 6-mercaptopurine use was associated with cancer (OR 10.8, CI 1.1-108.7). In conclusion, proximal small bowel disease, 6-mercaptopurine use, and hazardous occupations are associated with cancer of the small bowel in patients with Crohn's disease and can be added to the list of suspected risk factors.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01296557

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Digitale Medien

Hazard rates for dysplasia and cancer in ulcerative colitis (1989)

Lashner, Bret A. ; Silverstein, Marc D. ; Hanauer, Stephen B.

Springer

Digestive diseases and sciences 34 (1989), S. 1536-1541

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1573-2568

Schlagwort(e): cancer risk ; ulcerative colitis ; surveillance program ; hazard rates ; risk factors

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The risk of colon cancer in patients with ulcerative colitis is related to the duration and extent of disease. Prior reports have suggested that patients with onset of disease in childhood have a high risk of cancer. These risk factors were analyzed in 99 patients in a surveillance program of annual colonoscopy to detect mucosal dysplasia. All patients had pancolitis for at least eight years. The mean age at symptom onset was 23.2 years and the mean duration of disease at entry was 17 years. An average of 4.2 tests/patient were performed, and 91% were completely followed through 1985. Cancer risk was expressed as the hazard rate or the annual probability that a patient free of cancer would develop cancer after survival to a given time period. The hazard rate for high-grade dysplasia or cancer in patients with pancolitis measured from symptom onset was 2.5% at 20 years, 4% at 25 years, 7% at 30 years, 13% at 35 years, and 20% at 40 years. Sex was not a significant predictor of cancer, but older age at symptom onset was a predictor of dysplasia and cancer. From these data, the annual hazard rate of developing high-grade dysplasia or cancer can be estimated in patients with pancolitis based on an individual's age at symptom onset and duration of disease.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01537106

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Digitale Medien

Oil-assisted agglomeration for toner deinking: Population balance model and experiments (1997)

Snyder, Bret A. ; Berg, John C.

Hoboken, NJ : Wiley-Blackwell

AIChE Journal 43 (1997), S. 1480-1487

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 0001-1541

Schlagwort(e): Chemistry ; Chemical Engineering

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: This study examines the selective agglomeration of hydrophobic toner particles from a repulped paper fiber slurry by adding an immiscible oil that preferentially wets the toner particles. Effects of cationic starch additives, agitation rate, time, temperature and oil composition are examined experimentally in terms of the dynamic and steady-state evolution of the particle-size distribution produced. A simple, but effective, population balance model is solved numerically to simulate the agglomeration process and provides quantitative relationships between process variables and the effectiveness and rate of agglomeration. These relations are simple and clear. The process is shown to be controlled by the composite effect of the aforementioned variables on the aggregation and breakup rates, and the observed hehavior is understood in these terms. Practical recommendations for agglomeration, a process potentially useful for deinking toner-printed paper, are deduced from the results.

Zusätzliches Material: 7 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/aic.690430611

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 3 | 3 Treffer