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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    International journal of clinical oncology 4 (1999), S. 390-394 
    ISSN: 1437-7772
    Schlagwort(e): Key words Round cell sarcoma ; PNET ; Ewing's sarcoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background. The role of surgical intervention for the treatment of small round cell sarcoma of bone, has become important. However, there have been few reports concerning the surgical safety margin for this disease. An appropriate surgical margin should be discussed in relation to the effects of preoperative treatment, local recurrence rate, and prognosis. Methods. Twenty-eight patients with small round cell sarcoma of the bone were studied. Nineteen patients were stage M0 (of whom 18 were operated) and 9 were stage M1 (of whom 4 were operated). Preoperative treatment was evaluated by histological examination of the surgical specimen. The surgical margin was evaluated as curative, wide, marginal, or intralesional, by methods accepted by the Japanese Orthopedic Association. Results. (1) Of the 18 operated patients in stage M0, 2 showed local recurrence because of an inappropriate surgical margin or poor response to preoperative treatment. (2) Patients who had a wide margin procedure and who responded to preoperative treatment did not show local recurrence. (3) Patients who had a curative procedure did not show local recurrence regardless of the effect of preoperative treatment. (4) Patients with surgical speciment histologically evaluated as showing over 90% necrosis showed no local recurrences and had favorable prognoses with wide or curative procedures. Conclusion. The effects of preoperative treatment and surgical margins were important prognostic factors for local control in patients with small round cell sarcoma of the bone.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Journal of orthopaedic science 3 (1998), S. 225-238 
    ISSN: 1436-2023
    Schlagwort(e): Key words: soft tissue tumor ; clinical diagnosis ; medical images ; aspiration cytology ; biopsy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract: In the clinical diagnosis of a soft tissue tumor, it is important to determine whether the lesion is malignant as soon as possible. To establish such a diagnosis we perform aspiration cytology and needle biopsy simultaneously with computed radiography (CR) and echosonogram at the first visit. After the first day's investigations, it is usually possible to select the surgical procedures based on the working diagnosis in almost all patients. When the lesion is clearly benign by diagnosis, excision can be performed. For large lesions or lesions that are suspected to be malignant, CT, magnetic resonance imaging , isotope-investigation, and arteriography are also performed, effectively providing precision in an already established diagnosis. These imaging findings are useful for establishing a surgical plan by anticipating the surgical line of the safety margin. For these few patients in whom the diagnosis still remains uncertain or when preoperative treatment is planned, an incisional or excisional biopsy may be necessary to establish the final diagnosis. When preoperative treatment is performed, the effectiveness of this treatment can be evaluated by medical imaging.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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