ISSN:
1573-0646
Keywords:
6-thioguanine
;
phase II
;
small cell lung cancer
;
chemotherapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract Nineteen eligible patients with recurrent small cell lung cancer were treated with a 120 hour continuous infusion of 6-thioquanine at a starting dose of 35 mg/m2/day. There were no responses in these 19 patients. Toxicity was acceptable with the primary toxicity being hematologic. Based on this trial, 6-thioquanine is not felt to have significant antitumor activity in this patient population.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00873917